Substance P (free acid)
Substance P (free acid) structure
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Common Name | Substance P (free acid) | ||
|---|---|---|---|---|
| CAS Number | 71977-09-8 | Molecular Weight | 1348.61000 | |
| Density | 1.41 g/cm3 | Boiling Point | N/A | |
| Molecular Formula | C63H97N17O14S | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
Use of Substance P (free acid)Substance P, Free Acid is a native substance P analog, but shows no biological activity of substance P. |
| Name | substance p |
|---|---|
| Synonym | More Synonyms |
| Description | Substance P, Free Acid is a native substance P analog, but shows no biological activity of substance P. |
|---|---|
| Related Catalog | |
| References |
| Density | 1.41 g/cm3 |
|---|---|
| Molecular Formula | C63H97N17O14S |
| Molecular Weight | 1348.61000 |
| Exact Mass | 1347.71000 |
| PSA | 536.14000 |
| LogP | 4.09310 |
| Storage condition | 2-8℃ |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
|---|---|
| RIDADR | NONH for all modes of transport |
| Precursor 4 | |
|---|---|
| DownStream 0 | |
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Synthesis of potent antagonists of substance P by modifying the methionyl and glutaminyl residues of its C-terminal hexapeptide and without using D-amino acids.
Int. J. Pept. Protein Res. 41 , 411-414, (1993) Analogues of [Orn6]-SP6-11 have been synthesized in which the Met11-NH2 residue is replaced by the alpha, gamma-dimethyl, alpha, gamma-dibenzyl and alpha, gamma-di-tert-butyl esters of glutamic acid. ... |
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Synthesis of peptides by the solid-phase method. 7. Substance P and analogues.
J. Med. Chem. 25 , 64, (1982) Substance P and 21 related peptides containing isosteric or isofunctional groups were prepared by the solid-phase method. After purification by gel filtration and ion-exchange chromatography, the comp... |
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Biological activity of substance P methyl ester.
Mol. Pharmacol. 20 , 457, (1981)
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| H-ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET-OH |
| RPKPQQFFGLM |
| H-RPKPQQFFGLM-OH |
| RPKPQQFFGLM-OH |
| [Met-OH11] substance P |
| ARG-PRO-LYS-PRO-GLN-GLN-PHE-PHE-GLY-LEU-MET |
| Substance P, free acid |
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