Phenacetin-13C structure
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Common Name | Phenacetin-13C | ||
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CAS Number | 72156-72-0 | Molecular Weight | 180.20800 | |
Density | 1.099g/cm3 | Boiling Point | N/A | |
Molecular Formula | C10H13NO2 | Melting Point | 134-136ºC(lit.) | |
MSDS | Chinese USA | Flash Point | N/A | |
Symbol |
GHS07, GHS08 |
Signal Word | Danger |
Use of Phenacetin-13CPhenacetin-13C is the 13C labeled Phenacetin[1]. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[2][3][4]. |
Name | N-(4-ethoxyphenyl)acetamide |
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Synonym | More Synonyms |
Description | Phenacetin-13C is the 13C labeled Phenacetin[1]. Phenacetin (Acetophenetidin) is a non-opioid analgesic/antipyretic agent. Phenacetin is a selective COX-3 inhibitor. Phenacetin is used as probe of cytochrome P450 enzymes CYP1A2 in human liver microsomes and in rats[2][3][4]. |
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Related Catalog | |
In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
References |
Density | 1.099g/cm3 |
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Melting Point | 134-136ºC(lit.) |
Molecular Formula | C10H13NO2 |
Molecular Weight | 180.20800 |
Exact Mass | 180.09800 |
PSA | 38.33000 |
LogP | 2.11670 |
Index of Refraction | 1.548 |
Symbol |
GHS07, GHS08 |
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Signal Word | Danger |
Hazard Statements | H302-H350 |
Precautionary Statements | P201-P308 + P313 |
Hazard Codes | T: Toxic; |
Risk Phrases | 45-46-20/21/22 |
Safety Phrases | 53-22-36/37/39-45 |
RIDADR | UN 3077 9 / PGIII |
~96% Phenacetin-13C CAS#:72156-72-0 |
Literature: Kurumaya; Kajiwara; Abei; Hirano; Kokubun Chemical and pharmaceutical bulletin, 1988 , vol. 36, # 7 p. 2679 - 2681 |
~73% Phenacetin-13C CAS#:72156-72-0 |
Literature: Kurumaya; Kajiwara; Abei; Hirano; Kokubun Chemical and pharmaceutical bulletin, 1988 , vol. 36, # 7 p. 2679 - 2681 |
~% Phenacetin-13C CAS#:72156-72-0 |
Literature: Kurumaya; Kajiwara; Abei; Hirano; Kokubun Chemical and pharmaceutical bulletin, 1988 , vol. 36, # 7 p. 2679 - 2681 |
~% Phenacetin-13C CAS#:72156-72-0 |
Literature: Kurumaya; Kajiwara; Abei; Hirano; Kokubun Chemical and pharmaceutical bulletin, 1988 , vol. 36, # 7 p. 2679 - 2681 |
Precursor 4 | |
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DownStream 0 |
Gastroenterology 72 , 1033, (1977)
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N-(4-Ethoxy-1-13C-phenyl)acetamide |
MFCD00083951 |
N-4-((1-13C)Ethoxy)phenylacetamide |
Phenacetin-13C1 (ethoxy-1-13C) |
p-Acetophenetidide-ethoxy-1-13C |
(<1-13C>ethoxy)phenacetin |
Phenacetin-ethoxy-1-13C |