swainsonine structure
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Common Name | swainsonine | ||
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CAS Number | 72741-87-8 | Molecular Weight | 173.210 | |
Density | 1.38±0.1 g/cm3 | Boiling Point | 353.3±21.0 °C at 760 mmHg | |
Molecular Formula | C8H15NO3 | Melting Point | 144-145 ºC | |
MSDS | Chinese USA | Flash Point | 209.7±20.7 °C | |
Symbol |
GHS07 |
Signal Word | Warning |
Use of swainsonineSwainsonine is an alkaloid isolated from Astragalus, acts as an inhibitor of α-mannosidase, with anti-tumor activity[1]. |
Name | swainsonine |
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Synonym | More Synonyms |
Description | Swainsonine is an alkaloid isolated from Astragalus, acts as an inhibitor of α-mannosidase, with anti-tumor activity[1]. |
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Related Catalog | |
References |
Density | 1.38±0.1 g/cm3 |
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Boiling Point | 353.3±21.0 °C at 760 mmHg |
Melting Point | 144-145 ºC |
Molecular Formula | C8H15NO3 |
Molecular Weight | 173.210 |
Flash Point | 209.7±20.7 °C |
Exact Mass | 173.105194 |
PSA | 63.93000 |
LogP | -0.79 |
Vapour Pressure | 0.0±1.8 mmHg at 25°C |
Index of Refraction | 1.609 |
Storage condition | 2-8°C |
Water Solubility | Freely soluble (170 g/L) (25 ºC) |
Symbol |
GHS07 |
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Signal Word | Warning |
Hazard Statements | H302-H312-H332 |
Precautionary Statements | P280 |
Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
Hazard Codes | Xn: Harmful; |
Risk Phrases | R20/21/22 |
Safety Phrases | 36 |
RIDADR | NONH for all modes of transport |
WGK Germany | 3 |
RTECS | NM2408666 |
HS Code | 29339900 |
Precursor 9 | |
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DownStream 0 |
Production, HPLC analysis, and in situ apoptotic activities of swainsonine toward lepidopteran, Sf-21 cell line.
Biotechnol. Prog. 30(5) , 1196-205, (2014) Swainsonine, a secondary metabolite from Metarhizium anisopliae has been extensively studied in the complementary areas of therapeutics and toxicology. This work aims to develop a simple UV-HPLC metho... |
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DrugBank 3.0: a comprehensive resource for 'omics' research on drugs.
Nucleic Acids Res. 39 , D1035-41., (2011) DrugBank (http://www.drugbank.ca) is a richly annotated database of drug and drug target information. It contains extensive data on the nomenclature, ontology, chemistry, structure, function, action, ... |
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Swainsonine inhibits growth and potentiates the cytotoxic effect of paclitaxel in hepatocellular carcinoma in vitro and in vivo.
Oncol. Rep. 28(6) , 2091-100, (2012) Swainsonine, an extract from Astragalus membranaceus, exhibits broad inhibition of growth and pro-apoptotic activity in a number of tumor types. However, the underlying mechanism involved remains uncl... |
D-Swainsonine |
(1S,2R,8R,8aR)-Octahydroindolizine-1,2,8-triol |
(1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol |
1,2,8-Indolizinetriol, octahydro-, (1S,2R,8R,8aR)- |
8A,B-INDOLIZIDINE-1,2A,8B-TRIOL |
Tridolgosir |
SwainMoia |
UNII-RSY4RK37KQ |
swainsonine synthetic |
Swainsonine |
MFCD00017554 |