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72741-87-8

72741-87-8 structure
72741-87-8 structure
  • Name: swainsonine
  • Chemical Name: swainsonine
  • CAS Number: 72741-87-8
  • Molecular Formula: C8H15NO3
  • Molecular Weight: 173.210
  • Catalog: Natural product Alkaloid
  • Create Date: 2018-09-27 14:45:46
  • Modify Date: 2024-01-02 20:01:11
  • Swainsonine is an alkaloid isolated from Astragalus, acts as an inhibitor of α-mannosidase, with anti-tumor activity[1].

Name swainsonine
Synonyms D-Swainsonine
(1S,2R,8R,8aR)-Octahydroindolizine-1,2,8-triol
(1S,2R,8R,8aR)-Octahydro-1,2,8-indolizinetriol
1,2,8-Indolizinetriol, octahydro-, (1S,2R,8R,8aR)-
8A,B-INDOLIZIDINE-1,2A,8B-TRIOL
Tridolgosir
SwainMoia
UNII-RSY4RK37KQ
swainsonine synthetic
Swainsonine
MFCD00017554
Description Swainsonine is an alkaloid isolated from Astragalus, acts as an inhibitor of α-mannosidase, with anti-tumor activity[1].
Related Catalog
References

[1]. Silveira CRF, et al. Swainsonine, an alpha-mannosidase inhibitor, may worsen cervical cancer progression through the increase in myeloid derived suppressor cells population. PLoS One. 2019 Mar 6;14(3):e0213184.

Density 1.38±0.1 g/cm3
Boiling Point 353.3±21.0 °C at 760 mmHg
Melting Point 144-145 ºC
Molecular Formula C8H15NO3
Molecular Weight 173.210
Flash Point 209.7±20.7 °C
Exact Mass 173.105194
PSA 63.93000
LogP -0.79
Vapour Pressure 0.0±1.8 mmHg at 25°C
Index of Refraction 1.609
Storage condition 2-8°C
Water Solubility Freely soluble (170 g/L) (25 ºC)
Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H312-H332
Precautionary Statements P280
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xn: Harmful;
Risk Phrases R20/21/22
Safety Phrases 36
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS NM2408666
HS Code 29339900