ANSAMITOCIN DERIV

Modify Date: 2024-01-09 14:41:36

ANSAMITOCIN DERIV Structure
ANSAMITOCIN DERIV structure
Common Name ANSAMITOCIN DERIV
CAS Number 72902-38-6 Molecular Weight 621.11800
Density 1.33g/cm3 Boiling Point 845.8ºC at 760mmHg
Molecular Formula C31H41ClN2O9 Melting Point N/A
MSDS N/A Flash Point 465.3ºC

 Use of ANSAMITOCIN DERIV


20-O-Demethyl-AP3 is a minor metabolite of Ansamitocin P-3. Ansamitocin P-3, a microtubule inhibitor, is a macrocyclic antitumor antibiotic[1].

 Names

Name Maytansine, 2'-de(acetylmethylamino)-O(20)-demethyl-2'-methyl

 ANSAMITOCIN DERIV Biological Activity

Description 20-O-Demethyl-AP3 is a minor metabolite of Ansamitocin P-3. Ansamitocin P-3, a microtubule inhibitor, is a macrocyclic antitumor antibiotic[1].
Related Catalog
References

[1]. Zhongfa Liu, et al. Metabolism studies of the anti-tumor agent maytansine and its analog ansamitocin P-3 using liquid chromatography/tandem mass spectrometry. J Mass Spectrom. 2005 Mar;40(3):389-99.

 Chemical & Physical Properties

Density 1.33g/cm3
Boiling Point 845.8ºC at 760mmHg
Molecular Formula C31H41ClN2O9
Molecular Weight 621.11800
Flash Point 465.3ºC
Exact Mass 620.25000
PSA 147.16000
LogP 4.41440