3-Methyl-2-quinoxalinecarboxylic acid

Modify Date: 2024-01-06 13:53:48

3-Methyl-2-quinoxalinecarboxylic acid Structure
3-Methyl-2-quinoxalinecarboxylic acid structure
Common Name 3-Methyl-2-quinoxalinecarboxylic acid
CAS Number 74003-63-7 Molecular Weight 188.183
Density 1.4±0.1 g/cm3 Boiling Point 347.1±37.0 °C at 760 mmHg
Molecular Formula C10H8N2O2 Melting Point 168-170ºC
MSDS Chinese USA Flash Point 163.7±26.5 °C
Symbol GHS07
GHS07
Signal Word Warning

 Use of 3-Methyl-2-quinoxalinecarboxylic acid


3-Methyl-2-quinoxalinecarboxylic acid (MQCA), an important N-oxide reductive metabolite of Quinocetone or Olaquindox, potently inhibits the growth of Chang liver cells through S phase arrest of the cell cycle[1].

 Names

Name 3-methylquinoxaline-2-carboxylic acid
Synonym More Synonyms

 3-Methyl-2-quinoxalinecarboxylic acid Biological Activity

Description 3-Methyl-2-quinoxalinecarboxylic acid (MQCA), an important N-oxide reductive metabolite of Quinocetone or Olaquindox, potently inhibits the growth of Chang liver cells through S phase arrest of the cell cycle[1].
Related Catalog
References

[1]. Keyu Zhang , et al. Cytotoxicity and Genotoxicity of 1,4-bisdesoxyquinocetone, 3-methylquinoxaline-2-carboxylic Acid (MQCA) in Human Hepatocytes. Res Vet Sci. 2012 Dec;93(3):1393-401.

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 347.1±37.0 °C at 760 mmHg
Melting Point 168-170ºC
Molecular Formula C10H8N2O2
Molecular Weight 188.183
Flash Point 163.7±26.5 °C
Exact Mass 188.058578
PSA 63.08000
LogP 2.26
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.673
Storage condition -20°C Freezer

 Safety Information

Symbol GHS07
GHS07
Signal Word Warning
Hazard Statements H302-H319-H335
Precautionary Statements P261-P305 + P351 + P338
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Gloves
Hazard Codes Xi: Irritant;
Risk Phrases 22-36/37
Safety Phrases 26
RIDADR NONH for all modes of transport
HS Code 2933990090

 Synthetic Route

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Synonyms

3-Methyl-quinoxaline-2-carboxylic acid
2-Methyl-3-carboxy-chinoxalin
3-Methylchinoxalin-2-carbonsaeure
methylquinoxalinecarboxylicacid
3-Methyl-2-quinoxalinecarboxylic acid
3-methylquinoxaline-2-carboxylic acid
2-Quinoxalinecarboxylic acid, 3-methyl-
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