5-Carboxamidotryptamine maleate
5-Carboxamidotryptamine maleate structure
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Common Name | 5-Carboxamidotryptamine maleate | ||
|---|---|---|---|---|
| CAS Number | 74885-72-6 | Molecular Weight | 319.31 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C15H17N3O5 | Melting Point | N/A | |
| MSDS | USA | Flash Point | N/A | |
| Symbol |
GHS07 |
Signal Word | Warning | |
Use of 5-Carboxamidotryptamine maleate5-Carboxamidotryptamine maleate (5-CT maleate) is a potent 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5 and 5-HT7 receptors agonist[1][2][3]. |
| Name | 5-Carboxamidotryptamine maleate |
|---|---|
| Synonym | More Synonyms |
| Description | 5-Carboxamidotryptamine maleate (5-CT maleate) is a potent 5-HT1A, 5-HT1B, 5-HT1D, 5-HT5 and 5-HT7 receptors agonist[1][2][3]. |
|---|---|
| Related Catalog | |
| Target |
5-HT1A Receptor 5-HT1B Receptor 5-HT1D Receptor 5-HT5 Receptor 5-HT7 Receptor |
| In Vitro | [3H]-5-Carboxamidotryptamine (5-CT) binding to 5-HT1D sites in bovine substantia nigra is rapid, reversible and saturable, displaying high affinity (Kd = 0.38 nM) and low non-specific binding[2]. In bovine substantia nigra, [3H]-5-Carboxamidotryptamine (5-CT) labelled an equivalent number of binding sites to [3H]-5-Carboxamidotryptamine (403 and 362 fmol/mg protein, respectively) and binding is sensitive to guanine nucleotides[2]. |
| In Vivo | Topical 5-Carboxamidotryptamine (0.01-1000 μM) to the exposed dura mater encephala produced decreases in diastolic blood pressure, variable changes in meningeal blood flow and increases in conductance (i.e. dilatation) in the middle meningeal artery of anesthetized Wistar rats (serotonin depletion and treated with 20 mg/kg corticosterone)[1]. |
| References |
| Molecular Formula | C15H17N3O5 |
|---|---|
| Molecular Weight | 319.31 |
| Storage condition | -20°C |
| Symbol |
GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H315-H319-H335 |
| Precautionary Statements | P261-P305 + P351 + P338 |
| Personal Protective Equipment | dust mask type N95 (US);Eyeshields;Gloves |
| Hazard Codes | Xi |
| RIDADR | NONH for all modes of transport |
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| MFCD00069224 |