2-Chloro-6-Methoxypurine-9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside

Modify Date: 2024-01-28 18:06:11

2-Chloro-6-Methoxypurine-9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside Structure
2-Chloro-6-Methoxypurine-9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside structure
Common Name 2-Chloro-6-Methoxypurine-9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside
CAS Number 758705-70-3 Molecular Weight 318.69
Density 1.9±0.1 g/cm3 Boiling Point 547.9±60.0 °C at 760 mmHg
Molecular Formula C11H12ClFN4O4 Melting Point N/A
MSDS N/A Flash Point 285.2±32.9 °C

 Use of 2-Chloro-6-Methoxypurine-9-beta-D-(2'-deoxy-2'-fluoro)-arabinoriboside


2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine
Synonym More Synonyms

  Biological Activity

Description 2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Density 1.9±0.1 g/cm3
Boiling Point 547.9±60.0 °C at 760 mmHg
Molecular Formula C11H12ClFN4O4
Molecular Weight 318.69
Flash Point 285.2±32.9 °C
Exact Mass 318.053101
LogP 1.21
Vapour Pressure 0.0±1.5 mmHg at 25°C
Index of Refraction 1.736

 Synonyms

MFCD25542515
9H-Purine, 2-chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-
2-Chloro-9-(2-deoxy-2-fluoro-β-D-arabinofuranosyl)-6-methoxy-9H-purine
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