norastemizole

Modify Date: 2024-01-31 09:29:25

norastemizole Structure
norastemizole structure
Common Name norastemizole
CAS Number 75970-99-9 Molecular Weight 324.40
Density 1.28g/cm3 Boiling Point 519.8ºC at 760 mmHg
Molecular Formula C19H21FN4 Melting Point N/A
MSDS N/A Flash Point 268.2ºC

 Use of norastemizole


Tecastemizole (Norastemizole), a major metabolite of Astemizole, is a potent and selective H1 receptor antagonist. Tecastemizole shows anti-inflammatory activities[1].

 Names

Name 1-[(4-fluorophenyl)methyl]-N-piperidin-4-ylbenzimidazol-2-amine
Synonym More Synonyms

 norastemizole Biological Activity

Description Tecastemizole (Norastemizole), a major metabolite of Astemizole, is a potent and selective H1 receptor antagonist. Tecastemizole shows anti-inflammatory activities[1].
Related Catalog
References

[1]. Lever R, et al. Effect of tecastemizole on pulmonary and cutaneous allergic inflammatory responses. Clin Exp Allergy. 2007 Jun;37(6):909-17.

 Chemical & Physical Properties

Density 1.28g/cm3
Boiling Point 519.8ºC at 760 mmHg
Molecular Formula C19H21FN4
Molecular Weight 324.40
Flash Point 268.2ºC
Exact Mass 324.17500
PSA 45.11000
LogP 3.13830
Index of Refraction 1.658
Storage condition 2-8°C

 Synthetic Route

 Synonyms

T 1348
Tetemizole
Soltara
Norastemizole
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