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75970-99-9

75970-99-9 structure
75970-99-9 structure
  • Name: norastemizole
  • Chemical Name: 1-[(4-fluorophenyl)methyl]-N-piperidin-4-ylbenzimidazol-2-amine
  • CAS Number: 75970-99-9
  • Molecular Formula: C19H21FN4
  • Molecular Weight: 324.40
  • Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
  • Create Date: 2017-04-22 17:06:30
  • Modify Date: 2024-01-31 09:29:25
  • Tecastemizole (Norastemizole), a major metabolite of Astemizole, is a potent and selective H1 receptor antagonist. Tecastemizole shows anti-inflammatory activities[1].

Name 1-[(4-fluorophenyl)methyl]-N-piperidin-4-ylbenzimidazol-2-amine
Synonyms T 1348
Tetemizole
Soltara
Norastemizole
Description Tecastemizole (Norastemizole), a major metabolite of Astemizole, is a potent and selective H1 receptor antagonist. Tecastemizole shows anti-inflammatory activities[1].
Related Catalog
References

[1]. Lever R, et al. Effect of tecastemizole on pulmonary and cutaneous allergic inflammatory responses. Clin Exp Allergy. 2007 Jun;37(6):909-17.

Density 1.28g/cm3
Boiling Point 519.8ºC at 760 mmHg
Molecular Formula C19H21FN4
Molecular Weight 324.40
Flash Point 268.2ºC
Exact Mass 324.17500
PSA 45.11000
LogP 3.13830
Index of Refraction 1.658
Storage condition 2-8°C