Lavoltidine

Modify Date: 2024-01-12 16:49:28

Lavoltidine structure	Common Name	Lavoltidine
	CAS Number	76956-02-0	Molecular Weight	359.46600
	Density	1.23g/cm3	Boiling Point	566.9ºC at 760 mmHg
	Molecular Formula	C₁₉H₂₉N₅O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	296.6ºC

Use of Lavoltidine

Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia[1].

Name	loxtidine
Synonym	More Synonyms

Description	Lavoltidine (Loxtidine) is an an orally active, irreversible and highly potent histamine H2-receptor antagonist. Lavoltidine strongly inhibits gastric acid secretion and also induces hypergastrinemia[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Immunology/Inflammation >> Histamine Receptor Signaling Pathways >> GPCR/G Protein >> Histamine Receptor
Target	H2 Receptor
In Vivo	Lavoltidine (Loxtidine; 0.5 g/L; orally (drinking water); changed weekly; for 3 months) shows partial suppression of both gastric acid secretion and progression to neoplasia. Lavoltidine inhibits gastric atrophy, hyperplasia, and dysplasia in H felis-infected INS-GAS mice[1]. Lavoltidine treatment for 6 months inhibits gastric tumors in H felis-infected INS-GAS mice[1]. Animal Model: Male hypergastrinemic mice (INS-GAS mice) infected with Helicobacter felis[1] Dosage: 0.5 g/L Administration: Orally (drinking water); changed weekly; for 3 months Result: Showed partial suppression of both gastric acid secretion and progression to neoplasia.
References	[1]. Takaishi S, et al. Synergistic inhibitory effects of gastrin and histamine receptor antagonists on Helicobacter-induced gastric cancer.

Density	1.23g/cm3
Boiling Point	566.9ºC at 760 mmHg
Molecular Formula	C₁₉H₂₉N₅O₂
Molecular Weight	359.46600
Flash Point	296.6ºC
Exact Mass	359.23200
PSA	75.44000
LogP	2.18520
Index of Refraction	1.614

LAVOLTIDINE

Lavoltidina

Lavoltidinum

[1-methyl-5-[3-[3-(piperidin-1-ylmethyl)phenoxy]propylamino]-1,2,4-triazol-3-yl]methanol

Loxtidinum

Loxtidina

Loxtidine

Lavoltidinum [INN-Latin]

Loxtidinum [Latin]

Lavoltidine [INN:BAN]

Loxtidina [Spanish]

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Lavoltidine
Price: Negotiable
Purity: 98.0%
Delivery: 10 Day
Contact: Huang
Email: sales@echemcloud.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: Lavoltidine
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

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