Tributyl citrate
Tributyl citrate structure
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Common Name | Tributyl citrate | ||
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| CAS Number | 77-94-1 | Molecular Weight | 360.45 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 389.8±9.0 °C at 760 mmHg | |
| Molecular Formula | C18H32O7 | Melting Point | ≥300 °C(lit.) | |
| MSDS | Chinese USA | Flash Point | 120.7±12.2 °C | |
Use of Tributyl citrateTributyl citrate is a citric acid ester. Tributyl citrate can be used as an excipient, such as plasticizer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2]. |
| Name | Tributyl citrate |
|---|---|
| Synonym | More Synonyms |
| Description | Tributyl citrate is a citric acid ester. Tributyl citrate can be used as an excipient, such as plasticizer. Pharmaceutical excipients, or pharmaceutical auxiliaries, refer to other chemical substances used in the pharmaceutical process other than pharmaceutical ingredients. Pharmaceutical excipients generally refer to inactive ingredients in pharmaceutical preparations, which can improve the stability, solubility and processability of pharmaceutical preparations. Pharmaceutical excipients also affect the absorption, distribution, metabolism, and elimination (ADME) processes of co-administered drugs[1][2]. |
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| Related Catalog | |
| References |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 389.8±9.0 °C at 760 mmHg |
| Melting Point | ≥300 °C(lit.) |
| Molecular Formula | C18H32O7 |
| Molecular Weight | 360.45 |
| Flash Point | 120.7±12.2 °C |
| Exact Mass | 360.214813 |
| PSA | 99.13000 |
| LogP | 4.68 |
| Vapour Pressure | 0.0±2.0 mmHg at 25°C |
| Index of Refraction | 1.465 |
| Water Solubility | insoluble |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Personal Protective Equipment | Eyeshields;Gloves |
|---|---|
| Hazard Codes | T: Toxic; |
| Risk Phrases | R25 |
| Safety Phrases | S26-S36/37/39-S45-S24/25 |
| RIDADR | UN 2811 6.1/PG 2 |
| WGK Germany | 3 |
| RTECS | TZ8608000 |
| HS Code | 2918150000 |
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Tributyl citrate CAS#:77-94-1 |
| Literature: Sakakura, Akira; Nakagawa, Shoko; Ishihara, Kazuaki Tetrahedron, 2006 , vol. 62, # 2-3 p. 422 - 433 |
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Detail
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| Literature: EP1849764 A1, ; Page/Page column 21-22 ; |
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Detail
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| Literature: Chemistry and Biodiversity, , vol. 9, # 4 p. 714 - 726 |
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Tributyl citrate CAS#:77-94-1 |
| Literature: Industrial and Engineering Chemistry, , vol. 47, p. 797 |
CAS#:77-90-7
CAS#:16544-70-0| HS Code | 2918150000 |
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| Summary | 2918150000. other salts and esters of citric acid. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:4ABXY(export license,certificate of inspection for goods inward,certificate of inspection for goods outwardexport license(processing trade),export license(border small volume trade)). MFN tariff:6.5%. General tariff:30.0% |
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Formulation considerations in the design of topical, polymeric film-forming systems for sustained drug delivery to the skin.
Eur. J. Pharm. Biopharm. 91 , 9-15, (2015) Polymeric film-forming systems (FFSs) are potential drug delivery systems for topical application to the skin. The FFSs form thin and transparent polymeric films in situ upon solvent evaporation. Thei... |
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Improved mechanical property and water resistance of zein films by plasticization with tributyl citrate.
J. Agric. Food Chem. 60(23) , 5988-93, (2012) Pure zein film is intrinsically rigid and brittle and lacks necessary mechanical properties for industrial processing. In addition, pure zein film is sensitive to high relative humidity, which limits ... |
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Development of sustained-release lipophilic calcium stearate pellets via hot melt extrusion.
Eur. J. Pharm. Biopharm. 79(3) , 635-45, (2011) The objective of this study was the development of retarded release pellets using vegetable calcium stearate (CaSt) as a thermoplastic excipient. The matrix carrier was hot melt extruded and pelletize... |
| 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tributyl ester |
| Tri-n-butyl citrate |
| Citric acid tri-n-butyl ester |
| EINECS 201-071-2 |
| MFCD00027217 |
| Citric acid, tributyl ester (8CI) |
| Tributyl citrate |
| tributyl 2-hydroxypropane-1,2,3-tricarboxylate |
- Shanghai Nianxing Industrial Co., Ltd
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- Product Name: Tributyl citrate
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- China
- Product Name: Tributyl Citrate
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