BECLOMETASONE DIPROPIONATE MONOHYDRATE
Modify Date: 2024-01-04 17:10:54
BECLOMETASONE DIPROPIONATE MONOHYDRATE structure
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Common Name | BECLOMETASONE DIPROPIONATE MONOHYDRATE | ||
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| CAS Number | 77011-63-3 | Molecular Weight | 687.21500 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C34H51ClO12 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of BECLOMETASONE DIPROPIONATE MONOHYDRATEBeclometasone dipropionate monohydrate, the prodrug of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate monohydrate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate monohydrate can be used for asthma [1][2]. |
| Name | [2-[(8S,9R,10S,11S,13S,14S,16S,17R)-9-chloro-11-hydroxy-10,13,16-trimethyl-3-oxo-17-propanoyloxy-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-17-yl]-2-oxoethyl] propanoate,hydrate |
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| Synonym | More Synonyms |
| Description | Beclometasone dipropionate monohydrate, the prodrug of Beclometasone, is an orally active and potent glucocorticoid recepter agonist. Beclometasone dipropionate monohydrate acts via a glucocorticoid receptor and suppresses inflammation and hyperproliferation. Beclometasone dipropionate monohydrate can be used for asthma [1][2]. |
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| Related Catalog | |
| In Vitro | Beclometasone dipropionate monohydrate (1-100 nM; 20 min) inhibits STAT-1 expression and reduces the levels of iNOS, ROS and NT generated by rhIL-17A in 16HBE cells[2]. Western Blot Analysis[2] Cell Line: 16HBE cells Concentration: 1, 10 and 100 nM Incubation Time: 20 min Result: Reduced the levels of iNOS, ROS and NT generated by rhIL-17A. |
| In Vivo | Beclometasone dipropionate monohydrate (150 µg/kg; nebulization; male BALB/c mice) relieves asthma and decreases total cell number and relative eosinophil number[1]. Animal Model: Male BALB/c mice with asthma[1] Dosage: 150 µg/kg Administration: Nebulization Result: Decreased total cell number and relative eosinophil number in BALF. |
| References |
| Molecular Formula | C34H51ClO12 |
|---|---|
| Molecular Weight | 687.21500 |
| Exact Mass | 686.30700 |
| PSA | 190.80000 |
| LogP | 4.98450 |
| 4H7L9AI22I |
| beclomethasone dipropionate monohydrate |
| UNII-4H7L9AI22I |