Abyssinone V

Modify Date: 2024-01-01 22:34:58

Abyssinone V Structure
Abyssinone V structure
Common Name Abyssinone V
CAS Number 77263-11-7 Molecular Weight 408.49
Density 1.22g/cm3 Boiling Point 619.8ºC at 760 mmHg
Molecular Formula C25H28O5 Melting Point N/A
MSDS N/A Flash Point 210.8ºC

 Use of Abyssinone V


Abyssinone V is a prenylated flavonoid with predicted anti-viral activity. Abyssinone V can be isolated from the stem bark of Erythrina melanacantha. Abyssinone V possesses good pharmacodynamics properties. Abyssinone V is predicted to be antivirals including anti-herpes (HSV) agent, with mechanisms comprising inhibition of polymerase, ATPase and membrane integrity[1][2].

 Names

Name abyssinone V
Synonym More Synonyms

 Abyssinone V Biological Activity

Description Abyssinone V is a prenylated flavonoid with predicted anti-viral activity. Abyssinone V can be isolated from the stem bark of Erythrina melanacantha. Abyssinone V possesses good pharmacodynamics properties. Abyssinone V is predicted to be antivirals including anti-herpes (HSV) agent, with mechanisms comprising inhibition of polymerase, ATPase and membrane integrity[1][2].
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References

[1]. Koch K, et al. Abyssinone V, a prenylated flavonoid isolated from the stem bark of Erythrina melanacantha increases oxidative stress and decreases stress resistance in Caenorhabditis elegans. J Pharm Pharmacol. 2019 Jun;71(6):1007-1016.  

[2]. Kwofie SK, et al. Identification of novel potential inhibitors of varicella-zoster virus thymidine kinase from ethnopharmacologic relevant plants through an in-silico approach. J Biomol Struct Dyn. 2022;40(23):12932-12947.  

 Chemical & Physical Properties

Density 1.22g/cm3
Boiling Point 619.8ºC at 760 mmHg
Molecular Formula C25H28O5
Molecular Weight 408.49
Flash Point 210.8ºC
Exact Mass 408.19400
PSA 86.99000
LogP 5.52730
Index of Refraction 1.615

 Synonyms

Abyssinone-V
5,7-dihydroxy-2-[4-hydroxy-3,5-bis(3-methylbut-2-enyl)phenyl]-2,3-dihydrochromen-4-one
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