UNII:3I7LZ8M32B

Modify Date: 2024-01-02 18:26:30

UNII:3I7LZ8M32B Structure
UNII:3I7LZ8M32B structure
Common Name UNII:3I7LZ8M32B
CAS Number 7730-20-3 Molecular Weight 222.216
Density 1.4±0.1 g/cm3 Boiling Point 450.7±45.0 °C at 760 mmHg
Molecular Formula C11H11FN2O2 Melting Point 280-285 °C (dec.)(lit.)
MSDS Chinese USA Flash Point 226.4±28.7 °C

 Use of UNII:3I7LZ8M32B


6-Fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase, produced a transient disruption of sleep in rats chronically implanted with EEG recording electrodes[1].

 Names

Name 6-Fluoro-DL-tryptophan
Synonym More Synonyms

 Chemical & Physical Properties

Density 1.4±0.1 g/cm3
Boiling Point 450.7±45.0 °C at 760 mmHg
Melting Point 280-285 °C (dec.)(lit.)
Molecular Formula C11H11FN2O2
Molecular Weight 222.216
Flash Point 226.4±28.7 °C
Exact Mass 222.080460
PSA 79.11000
LogP 1.09
Vapour Pressure 0.0±1.2 mmHg at 25°C
Index of Refraction 1.673
Storage condition −20°C

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
YN6850000
CHEMICAL NAME :
DL-Tryptophan, 6-fluoro-
CAS REGISTRY NUMBER :
7730-20-3
LAST UPDATED :
199612
DATA ITEMS CITED :
1
MOLECULAR FORMULA :
C11-H11-F-N2-O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
>1 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 15,2134,1966

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes T
Safety Phrases S24/25
RIDADR NONH for all modes of transport
WGK Germany 3
RTECS YN6850000
HS Code 2933990090

 Precursor & DownStream

Precursor  0

DownStream  1

 Customs

HS Code 2933990090
Summary 2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles29

More Articles
Substrate promiscuity of the cyclic dipeptide prenyltransferases from Aspergillus fumigatus ( section sign).

J. Nat. Prod. 72 , 44-52, (2009)

This study reports that a series of tryptophan derivatives with modifications on the side chain or at the indole ring were accepted by two cyclic dipeptide prenyltransferases, CdpNPT and FtmPT1, and c...

Cloning of the trp gene cluster from a tryptophan-hyperproducing strain of Corynebacterium glutamicum: identification of a mutation in the trp leader sequence.

Appl. Environ. Microbiol. 59(3) , 791-9, (1993)

Corynebacterium glutamicum ATCC 21850 produces up to 5 g of extracellular L-tryptophan per liter in broth culture and displays resistance to several synthetic analogs of aromatic amino acids. Here we ...

Atomic mutations at the single tryptophan residue of human recombinant annexin V: effects on structure, stability, and activity.

Biochemistry 38(33) , 10649-59, (1999)

The single tryptophan residue (Trp187) of human recombinant annexin V, containing 320 residues and 5328 atoms, was replaced with three different isosteric analogues where hydrogen atoms at positions 4...

 Synonyms

EINECS 231-788-6
Tryptophan, 6-fluoro-
2-Amino-3-(6-fluoro-1H-indol-3-yl)propanoic acid
6-Fluorotryptophan
6-fluoro-dl-tryptophan
MFCD00005653
UNII:3I7LZ8M32B