7730-20-3

7730-20-3 structure

Name: UNII:3I7LZ8M32B
Chemical Name: 6-Fluoro-DL-tryptophan
CAS Number: 7730-20-3
Molecular Formula: C₁₁H₁₁FN₂O₂
Molecular Weight: 222.216
Catalog: Biochemical Amino acids and their derivatives Tryptophan derivatives
Create Date: 2018-03-22 08:00:00
Modify Date: 2024-01-02 18:26:30
6-Fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase, produced a transient disruption of sleep in rats chronically implanted with EEG recording electrodes[1].

Name	6-Fluoro-DL-tryptophan
Synonyms	EINECS 231-788-6 Tryptophan, 6-fluoro- 2-Amino-3-(6-fluoro-1H-indol-3-yl)propanoic acid 6-Fluorotryptophan 6-fluoro-dl-tryptophan MFCD00005653 UNII:3I7LZ8M32B

Description	6-Fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase, produced a transient disruption of sleep in rats chronically implanted with EEG recording electrodes[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Tryptophan Hydroxylase Research Areas >> Neurological Disease
References	[1]. Miwa S, et al. Determination of serotonin turnover in the rat brain using 6-fluorotryptophan. J Neurochem. 1987 May;48(5):1577-80. [2]. D Sugden, et al. Changes in the rat sleep-wake cycle produced by DL-6-fluorotryptophan, a competitive inhibitor of tryptophan hydroxylase. Psychopharmacology (Berl). 1981;74(4):369-73.

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 15,2134,1966

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
Hazard Codes	T
Safety Phrases	S24/25
RIDADR	NONH for all modes of transport
WGK Germany	3
RTECS	YN6850000
HS Code	2933990090

Precursor 0
DownStream 1
138428-34-9

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%