Cholesterol-13C2
Modify Date: 2024-01-03 05:32:53
Cholesterol-13C2 structure
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Common Name | Cholesterol-13C2 | ||
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| CAS Number | 78887-48-6 | Molecular Weight | 388.63900 | |
| Density | 1.072 g/mL at 25ºC | Boiling Point | 360ºC(lit.) | |
| Molecular Formula | C2513C2H46O | Melting Point | 147-149ºC(lit.) | |
| MSDS | Chinese USA | Flash Point | N/A | |
Use of Cholesterol-13C2Cholesterol-13C2 is the 13C labeled Cholesterol. Cholesterol is the major sterol in mammals and is makes up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins[1][2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist[3]. |
| Name | (3S,8S,9S,10R,13R,14S,17R)-10,13-dimethyl-17-[(2R)-6-methylheptan-2-yl]-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol |
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| Synonym | More Synonyms |
| Description | Cholesterol-13C2 is the 13C labeled Cholesterol. Cholesterol is the major sterol in mammals and is makes up 20-25% of structural component of the plasma membrane. Plasma membranes are highly permeable to water but relatively impermeable to ions and protons. Cholesterol plays an important role in determining the fluidity and permeability characteristics of the membrane as well as the function of both the transporters and signaling proteins[1][2]. Cholesterol is also an endogenous estrogen-related receptor α (ERRα) agonist[3]. |
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| Related Catalog | |
| In Vitro | Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1]. |
| References |
| Density | 1.072 g/mL at 25ºC |
|---|---|
| Boiling Point | 360ºC(lit.) |
| Melting Point | 147-149ºC(lit.) |
| Molecular Formula | C2513C2H46O |
| Molecular Weight | 388.63900 |
| Exact Mass | 388.36200 |
| PSA | 20.23000 |
| LogP | 7.38870 |
| RIDADR | NONH for all modes of transport |
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~%
Cholesterol-13C2 CAS#:78887-48-6 |
| Literature: Steroids, , vol. 39, # 3 p. 279 - 290 |
| Precursor 1 | |
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| DownStream 0 | |
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Procollagen C-endopeptidase Enhancer Protein 2 (PCPE2) Reduces Atherosclerosis in Mice by Enhancing Scavenger Receptor Class B1 (SR-BI)-mediated High-density Lipoprotein (HDL)-Cholesteryl Ester Uptake.
J. Biol. Chem. 290 , 15496-511, (2015) Studies in human populations have shown a significant correlation between procollagen C-endopeptidase enhancer protein 2 (PCPE2) single nucleotide polymorphisms and plasma HDL cholesterol concentratio... |
| Cholesterol-3,4-13C2 |
| (13C2)-cholesterol |
| cholesterol-13C4,13C3 |