Sertraline hydrochloride
Modify Date: 2024-01-01 23:09:53
Sertraline hydrochloride structure
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Common Name | Sertraline hydrochloride | ||
|---|---|---|---|---|
| CAS Number | 79559-97-0 | Molecular Weight | 342.690 | |
| Density | N/A | Boiling Point | 416.3ºC at 760 mmHg | |
| Molecular Formula | C17H18Cl3N | Melting Point | 246-249°C | |
| MSDS | Chinese USA | Flash Point | 205.6ºC | |
| Symbol |
GHS02, GHS06, GHS08 |
Signal Word | Danger | |
Use of Sertraline hydrochlorideSertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.Target: SSRISertraline is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It was introduced to the market by Pfizer in 1991. Sertraline is primarily prescribed for major depressive disorder in adult outpatients as well as obsessive–compulsive, panic, and social anxiety disorders in both adults and children. In 2011, it was the second-most prescribed antidepressant on the U.S. retail market, with 37,208,000 prescriptions.Sertraline is used for a number of conditions including: major depression, obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder and social phobia (social anxiety disorder). It has also been used for premature ejaculation and vascular headaches but evidence of the effectiveness in treating those conditions is less robust. |
| Name | sertraline hydrochloride |
|---|---|
| Synonym | More Synonyms |
| Description | Sertraline hydrochloride is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class.Target: SSRISertraline is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. It was introduced to the market by Pfizer in 1991. Sertraline is primarily prescribed for major depressive disorder in adult outpatients as well as obsessive–compulsive, panic, and social anxiety disorders in both adults and children. In 2011, it was the second-most prescribed antidepressant on the U.S. retail market, with 37,208,000 prescriptions.Sertraline is used for a number of conditions including: major depression, obsessive-compulsive disorder (OCD), body dysmorphic disorder (BDD), posttraumatic stress disorder (PTSD), premenstrual dysphoric disorder (PMDD), panic disorder and social phobia (social anxiety disorder). It has also been used for premature ejaculation and vascular headaches but evidence of the effectiveness in treating those conditions is less robust. |
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| Related Catalog | |
| References |
| Boiling Point | 416.3ºC at 760 mmHg |
|---|---|
| Melting Point | 246-249°C |
| Molecular Formula | C17H18Cl3N |
| Molecular Weight | 342.690 |
| Flash Point | 205.6ºC |
| Exact Mass | 341.050476 |
| PSA | 12.03000 |
| LogP | 6.37250 |
| Storage condition | Desiccate at RT |
| Stability | Store in Freezer |
| Water Solubility | DMSO: ~26 mg/mL |
CHEMICAL IDENTIFICATION
HEALTH HAZARD DATAACUTE TOXICITY DATA
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| Symbol |
GHS02, GHS06, GHS08 |
|---|---|
| Signal Word | Danger |
| Hazard Statements | H225-H301 + H311 + H331-H370 |
| Precautionary Statements | P210-P260-P280-P301 + P310-P311 |
| Personal Protective Equipment | Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter |
| Hazard Codes | Xi |
| Risk Phrases | R36/37/38 |
| Safety Phrases | S22-S24/25 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | 3 |
| RTECS | QJ0352070 |
| HS Code | 2921300090 |
CAS#:79617-96-2
CAS#:244223-89-0
CAS#:836597-67-2
CAS#:64-19-7
CAS#:254731-40-3| HS Code | 2921499090 |
|---|---|
| Summary | 2921499090 other aromatic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0% |
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Ultrasound effects on brain-targeting mannosylated liposomes: in vitro and blood-brain barrier transport investigations.
Drug Des. Devel. Ther. 9 , 3885-98, (2015) Delivering drugs to intracerebral regions can be accomplished by improving the capacity of transport through blood-brain barrier. Using sertraline as model drug for brain targeting, the current study ... |
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Gingival pain: an unusual side effect of ziprasidone.
BMJ Case Rep. 2013 , doi:10.1136/bcr-2012-007577, (2013) The patient is a 52-year-old man with schizophrenia who developed severe, unremitting gingival pain after his ziprasidone dosage was increased from 80 to 120 mg. His physical examination and laborator... |
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Behavioral and biochemical responses in freshwater fish Carassius auratus exposed to sertraline.
Chemosphere 135 , 146-55, (2015) Sertraline is one of the most commonly prescribed selective serotonin reuptake inhibitors and is frequently detected in the aquatic environment. However, knowledge regarding relationships among molecu... |
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| EINECS 200-659-6 |
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| CP-51974-1 |
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| CP 51974-1 |
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| MFCD00895772 |
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| Lustral |
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