Azido-PEG1-CH2COO-Cl

Modify Date: 2024-01-09 10:42:05

Azido-PEG1-CH2COO-Cl structure	Common Name	Azido-PEG1-CH2COO-Cl
	CAS Number	79598-49-5	Molecular Weight	163.56
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₄H₆ClN₃O₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of Azido-PEG1-CH2COO-Cl

Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker. Azido-PEG1-CH2COO-Cl can be used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131)[1].

Name	Azido-PEG1-CH2COO-Cl

Description	Azido-PEG1-CH2COO-Cl (compound 43a) is an alkyl/ether-based PROTAC linker. Azido-PEG1-CH2COO-Cl can be used in the synthesis of PROTAC BRD4 Degrader-1 (HY-133131)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	Alkyl/ether
In Vitro	PROTAC BRD4 Degrader-1 is an efficacious BRD4 degrader with an IC50 of 41.8 nM against BRD4 BD1. PROTAC BRD4 Degrader-1 can effectively degrade BRD4 protein and suppress c-Myc expression[1].
References	[1]. Zhang F, et al. Discovery of a new class of PROTAC BRD4 degraders based on a dihydroquinazolinone derivative and lenalidomide/pomalidomide.Bioorg Med Chem. 2020 Jan 1;28(1):115228.

Molecular Formula	C₄H₆ClN₃O₂
Molecular Weight	163.56

Hazard Codes	Xi

Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Azido-PEG1-CH2COO-Cl
Price: Click To Check
Purity: 95.0%
Delivery: 10 Day
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