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1517-05-1

1517-05-1 structure
1517-05-1 structure
  • Name: Azido-PEG1
  • Chemical Name: 2-Azidoethanol
  • CAS Number: 1517-05-1
  • Molecular Formula: C17H16ClN5
  • Molecular Weight: 325.795
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2016-06-13 06:18:11
  • Modify Date: 2024-01-02 10:58:09
  • Azido-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 2-Azidoethanol
Synonyms 4-Chloro-6-[2-(diphenylmethyl)hydrazino]-5-pyrimidinamine
5-Pyrimidinamine, 4-chloro-6-[2-(diphenylmethyl)hydrazinyl]-
Description Azido-PEG1 is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Density 1.3±0.1 g/cm3
Boiling Point 411.7±45.0 °C at 760 mmHg
Molecular Formula C17H16ClN5
Molecular Weight 325.795
Flash Point 202.8±28.7 °C
Exact Mass 325.109436
PSA 69.98000
LogP 5.39
Vapour Pressure 0.0±1.0 mmHg at 25°C
Index of Refraction 1.698
HS Code 2929909090
HS Code 2929909090
Summary 2929909090 other compounds with other nitrogen function VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%