1392284-57-9

1392284-57-9 structure

Name: Azido-PEG11-azide
Chemical Name: 1,35-Diazido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontane
CAS Number: 1392284-57-9
Molecular Formula: C₂₄H₄₈N₆O₁₁
Molecular Weight: 596.672
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2018-07-10 23:04:03
Modify Date: 2024-01-09 21:11:34
Azido-PEG11-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	1,35-Diazido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontane
Synonyms	3,6,9,12,15,18,21,24,27,30,33-Undecaoxapentatriacontane, 1,35-diazido- 1,35-Diazido-3,6,9,12,15,18,21,24,27,30,33-undecaoxapentatriacontane

Description	Azido-PEG11-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562