12-(Azido)lauric acid

Modify Date: 2024-01-12 19:41:37

12-(Azido)lauric acid Structure
12-(Azido)lauric acid structure
Common Name 12-(Azido)lauric acid
CAS Number 80667-36-3 Molecular Weight 241.330
Density N/A Boiling Point N/A
Molecular Formula C12H23N3O2 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 12-(Azido)lauric acid


Azido Myristic Acid is a click chemistry reagent containing an azide group. Azido Myristic Acid can be used to identify and characterize post-translationally myristylated proteins with using a simple and robust two-step labeling and detection technique[1].

 Names

Name 12-azidododecanoic acid
Synonym More Synonyms

 12-(Azido)lauric acid Biological Activity

Description Azido Myristic Acid is a click chemistry reagent containing an azide group. Azido Myristic Acid can be used to identify and characterize post-translationally myristylated proteins with using a simple and robust two-step labeling and detection technique[1].
Related Catalog
In Vitro Azido Myristic Acid could be a suitable substrate for enzymes. Due to the very small size of the azide group and its complete absence in any natural molecules the presence of azide group does affect the biodistribution of azido palmitic acid in comparison to the natural palmitic acid making it a suitable substrate for enzymes.
References

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.  

 Chemical & Physical Properties

Molecular Formula C12H23N3O2
Molecular Weight 241.330
Exact Mass 241.179031
PSA 87.05000
LogP 3.93

 Synthetic Route

~99%

12-(Azido)lauric acid Structure

12-(Azido)lauri...

CAS#:80667-36-3

Literature: Grinstaff, Mark W.; Barthelemy, Philippe; Prata, Carla; Moreau, Louis Patent: US2006/241071 A1, 2006 ; Location in patent: Page/Page column 53-54 ;

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12-(Azido)lauric acid Structure

12-(Azido)lauri...

CAS#:80667-36-3

Literature: Hang, Howard C.; Geutjes, Ernst-Jan; Grotenbreg, Gijsbert; Pollington, Annette M.; Bijlmakers, Marie Jose; Ploegh, Hidde L. Journal of the American Chemical Society, 2007 , vol. 129, # 10 p. 2744 - 2745

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12-(Azido)lauric acid Structure

12-(Azido)lauri...

CAS#:80667-36-3

Literature: Hang, Howard C.; Geutjes, Ernst-Jan; Grotenbreg, Gijsbert; Pollington, Annette M.; Bijlmakers, Marie Jose; Ploegh, Hidde L. Journal of the American Chemical Society, 2007 , vol. 129, # 10 p. 2744 - 2745

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12-(Azido)lauric acid Structure

12-(Azido)lauri...

CAS#:80667-36-3

Literature: Hang, Howard C.; Geutjes, Ernst-Jan; Grotenbreg, Gijsbert; Pollington, Annette M.; Bijlmakers, Marie Jose; Ploegh, Hidde L. Journal of the American Chemical Society, 2007 , vol. 129, # 10 p. 2744 - 2745

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12-(Azido)lauric acid Structure

12-(Azido)lauri...

CAS#:80667-36-3

Literature: Washington University Patent: US5338858 A1, 1994 ;

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12-(Azido)lauric acid Structure

12-(Azido)lauri...

CAS#:80667-36-3

Literature: Garcia, Jordi; Vilarrasa, Jaume Tetrahedron Letters, 1987 , vol. 28, # 3 p. 341 - 342

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12-(Azido)lauric acid Structure

12-(Azido)lauri...

CAS#:80667-36-3

Literature: Garcia, Jordi; Vilarrasa, Jaume Tetrahedron Letters, 1987 , vol. 28, # 3 p. 341 - 342

 Synonyms

12-azido dodecanoic acid
12-(Azido)lauric acid
12-Azidododecanoic acid
Dodecanoic acid, 12-azido-
Click-iT.(R). Az-C12
Click-iT.(R). myristic acid
Dodecanoic acid,12-azido
12Az lauric acid
12AZ