80667-36-3

80667-36-3 structure
80667-36-3 structure
  • Name: 12-(Azido)lauric acid
  • Chemical Name: 12-azidododecanoic acid
  • CAS Number: 80667-36-3
  • Molecular Formula: C12H23N3O2
  • Molecular Weight: 241.330
  • Catalog: Research Areas Others
  • Create Date: 2017-07-10 19:54:33
  • Modify Date: 2024-01-12 19:41:37
  • Azido Myristic Acid is a click chemistry reagent containing an azide group. Azido Myristic Acid can be used to identify and characterize post-translationally myristylated proteins with using a simple and robust two-step labeling and detection technique[1].

Name 12-azidododecanoic acid
Synonyms 12-azido dodecanoic acid
12-(Azido)lauric acid
12-Azidododecanoic acid
Dodecanoic acid, 12-azido-
Click-iT.(R). Az-C12
Click-iT.(R). myristic acid
Dodecanoic acid,12-azido
12Az lauric acid
12AZ
Description Azido Myristic Acid is a click chemistry reagent containing an azide group. Azido Myristic Acid can be used to identify and characterize post-translationally myristylated proteins with using a simple and robust two-step labeling and detection technique[1].
Related Catalog
In Vitro Azido Myristic Acid could be a suitable substrate for enzymes. Due to the very small size of the azide group and its complete absence in any natural molecules the presence of azide group does affect the biodistribution of azido palmitic acid in comparison to the natural palmitic acid making it a suitable substrate for enzymes.
References

[1]. Jiang X, et al. Recent applications of click chemistry in drug discovery. Expert Opin Drug Discov. 2019 Aug;14(8):779-789.  

Molecular Formula C12H23N3O2
Molecular Weight 241.330
Exact Mass 241.179031
PSA 87.05000
LogP 3.93

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80667-36-3 structure

80667-36-3

Literature: Grinstaff, Mark W.; Barthelemy, Philippe; Prata, Carla; Moreau, Louis Patent: US2006/241071 A1, 2006 ; Location in patent: Page/Page column 53-54 ;

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80667-36-3 structure

80667-36-3

Literature: Hang, Howard C.; Geutjes, Ernst-Jan; Grotenbreg, Gijsbert; Pollington, Annette M.; Bijlmakers, Marie Jose; Ploegh, Hidde L. Journal of the American Chemical Society, 2007 , vol. 129, # 10 p. 2744 - 2745

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80667-36-3 structure

80667-36-3

Literature: Hang, Howard C.; Geutjes, Ernst-Jan; Grotenbreg, Gijsbert; Pollington, Annette M.; Bijlmakers, Marie Jose; Ploegh, Hidde L. Journal of the American Chemical Society, 2007 , vol. 129, # 10 p. 2744 - 2745

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80667-36-3 structure

80667-36-3

Literature: Hang, Howard C.; Geutjes, Ernst-Jan; Grotenbreg, Gijsbert; Pollington, Annette M.; Bijlmakers, Marie Jose; Ploegh, Hidde L. Journal of the American Chemical Society, 2007 , vol. 129, # 10 p. 2744 - 2745

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80667-36-3 structure

80667-36-3

Literature: Washington University Patent: US5338858 A1, 1994 ;

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80667-36-3 structure

80667-36-3

Literature: Garcia, Jordi; Vilarrasa, Jaume Tetrahedron Letters, 1987 , vol. 28, # 3 p. 341 - 342

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80667-36-3 structure

80667-36-3

Literature: Garcia, Jordi; Vilarrasa, Jaume Tetrahedron Letters, 1987 , vol. 28, # 3 p. 341 - 342