Indolapril hydrochloride [USAN]

Modify Date: 2024-02-21 19:13:15

Indolapril hydrochloride [USAN] Structure
Indolapril hydrochloride [USAN] structure
 Common Name Indolapril hydrochloride [USAN]
CAS Number 80828-32-6 Molecular Weight 466.99800
Density N/A Boiling Point N/A
Molecular Formula C24H35ClN2O5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Indolapril hydrochloride [USAN]


Indolapril hydrochloride (CI-907) is an orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor. Indolapril hydrochloride is highly specific in suppressing the contractile or pressor responses to Angiotensin I. Indolapril hydrochloride is a potent antihypertensive agent[1].

 Names

Name Indolapril hydrochloride
Synonym More Synonyms

 Indolapril hydrochloride [USAN] Biological Activity

Description Indolapril hydrochloride (CI-907) is an orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor. Indolapril hydrochloride is highly specific in suppressing the contractile or pressor responses to Angiotensin I. Indolapril hydrochloride is a potent antihypertensive agent[1].
Related Catalog
References

[1]. M J Ryan, et al. Antihypertensive effects of CI-907 (indolapril): a novel nonsulfhydryl angiotensin converting enzyme inhibitor. J Pharmacol Exp Ther. 1984 Feb;228(2):312-8.  

 Chemical & Physical Properties

Molecular Formula C24H35ClN2O5
Molecular Weight 466.99800
Exact Mass 466.22300
PSA 95.94000
LogP 3.90410

 Synonyms

(2S-(1-(R*(R*)),2α,3aβ,7aβ))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydro-1H-indole-2-carboxylic acid hydrochloride
indolapril Hydrochloride
{2S-[1-(R*(R*)),2α,3aβ,7aβ]}-1-(2-{[1-(ethoxycarbonyl)-3-phenylpropyl]amino}-1-oxopropyl)octahydro-1H-indole-2-carboxylic acid hydrochloride
[1-[(2R,3aS,7aS)-2-carboxy-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-1-oxopropan-2-yl]-(1-ethoxy-1-oxo-4-phenylbutan-2-yl)azanium chloride
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