80828-32-6

80828-32-6 structure

Name: Indolapril hydrochloride [USAN]
Chemical Name: Indolapril hydrochloride
CAS Number: 80828-32-6
Molecular Formula: C₂₄H₃₅ClN₂O₅
Molecular Weight: 466.99800
Catalog: Signaling Pathways Metabolic Enzyme/Protease Angiotensin-converting Enzyme (ACE)
Create Date: 2018-06-29 04:44:35
Modify Date: 2024-02-21 19:13:15
Indolapril hydrochloride (CI-907) is an orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor. Indolapril hydrochloride is highly specific in suppressing the contractile or pressor responses to Angiotensin I. Indolapril hydrochloride is a potent antihypertensive agent[1].

Name	Indolapril hydrochloride
Synonyms	(2S-(1-(R(R)),2α,3aβ,7aβ))-1-(2-((1-(ethoxycarbonyl)-3-phenylpropyl)amino)-1-oxopropyl)octahydro-1H-indole-2-carboxylic acid hydrochloride indolapril Hydrochloride {2S-[1-(R(R)),2α,3aβ,7aβ]}-1-(2-{[1-(ethoxycarbonyl)-3-phenylpropyl]amino}-1-oxopropyl)octahydro-1H-indole-2-carboxylic acid hydrochloride [1-[(2R,3aS,7aS)-2-carboxy-2,3,3a,4,5,6,7,7a-octahydroindol-1-yl]-1-oxopropan-2-yl]-(1-ethoxy-1-oxo-4-phenylbutan-2-yl)azanium chloride

Description	Indolapril hydrochloride (CI-907) is an orally active nonsulfhydryl angiotensin converting enzyme (ACE) inhibitor. Indolapril hydrochloride is highly specific in suppressing the contractile or pressor responses to Angiotensin I. Indolapril hydrochloride is a potent antihypertensive agent[1].
Related Catalog	Signaling Pathways >> Metabolic Enzyme/Protease >> Angiotensin-converting Enzyme (ACE) Research Areas >> Metabolic Disease
References	[1]. M J Ryan, et al. Antihypertensive effects of CI-907 (indolapril): a novel nonsulfhydryl angiotensin converting enzyme inhibitor. J Pharmacol Exp Ther. 1984 Feb;228(2):312-8.