PTP1B-IN-3

Modify Date: 2024-01-09 16:38:16

PTP1B-IN-3 Structure
PTP1B-IN-3 structure
Common Name PTP1B-IN-3
CAS Number 809272-64-8 Molecular Weight 362.06300
Density N/A Boiling Point N/A
Molecular Formula C12H7BrF2NO3P Melting Point N/A
MSDS N/A Flash Point N/A

 Use of PTP1B-IN-3


PTP1B-IN-3 is a potent and selective PTP1B inhibitor with IC50s of 120 nM (PTP1B) and 120 nM (TCPTP), respectively.

 Names

Name [(3-bromo-7-cyano-2-naphthyl)-(difluoro)methyl]phosphonic acid
Synonym More Synonyms

 PTP1B-IN-3 Biological Activity

Description PTP1B-IN-3 is a potent and selective PTP1B inhibitor with IC50s of 120 nM (PTP1B) and 120 nM (TCPTP), respectively.
Related Catalog
Target

IC50: 120 nM (PTP1B), 120 nM (TCPTP) [1].

References

[1]. Patel D, .Discovery of orally active, potent, and selective benzotriazole-based PTP1B inhibitors. ChemMedChem. 2011 Jun 6; 6(6):1011-6.

 Chemical & Physical Properties

Molecular Formula C12H7BrF2NO3P
Molecular Weight 362.06300
Exact Mass 360.93100
PSA 91.13000
LogP 3.70098

 Synonyms

P-[(3-Bromo-7-cyano-2-naphthalenyl)difluoromethyl]phosphonic Acid
PTP1B-IN-3
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