m-PEG5-nitrile

Modify Date: 2024-01-04 05:23:56

m-PEG5-nitrile Structure
m-PEG5-nitrile structure
Common Name m-PEG5-nitrile
CAS Number 81836-41-1 Molecular Weight 261.31
Density N/A Boiling Point N/A
Molecular Formula C12H23NO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of m-PEG5-nitrile


m-PEG5-nitrile is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

 Names

Name m-PEG5-nitrile

 m-PEG5-nitrile Biological Activity

Description m-PEG5-nitrile is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Saifer MG, et al. Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol. 2014 Feb;57(2):236-46.

 Chemical & Physical Properties

Molecular Formula C12H23NO5
Molecular Weight 261.31

 Safety Information

Hazard Codes Xi