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81836-41-1

81836-41-1 structure
81836-41-1 structure
  • Name: m-PEG5-nitrile
  • Chemical Name: m-PEG5-nitrile
  • CAS Number: 81836-41-1
  • Molecular Formula: C12H23NO5
  • Molecular Weight: 261.31
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2020-04-11 18:11:15
  • Modify Date: 2024-01-04 05:23:56
  • m-PEG5-nitrile is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.

Name m-PEG5-nitrile
Description m-PEG5-nitrile is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
Related Catalog
In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
References

[1]. Saifer MG, et al. Selectivity of binding of PEGs and PEG-like oligomers to anti-PEG antibodies induced by methoxyPEG-proteins. Mol Immunol. 2014 Feb;57(2):236-46.

Molecular Formula C12H23NO5
Molecular Weight 261.31
Hazard Codes Xi