Diiodohydroxyquinoline

Modify Date: 2024-01-02 16:16:01

Diiodohydroxyquinoline structure	Common Name	Diiodohydroxyquinoline
	CAS Number	83-73-8	Molecular Weight	396.951
	Density	2.5±0.1 g/cm3	Boiling Point	401.8±45.0 °C at 760 mmHg
	Molecular Formula	C₉H₅I₂NO	Melting Point	>200 °C (dec.)(lit.)
	MSDS	Chinese USA	Flash Point	196.8±28.7 °C
	Symbol	GHS05, GHS07	Signal Word	Danger

Use of Diiodohydroxyquinoline

Diiodohydroxyquinoline is a topical therapeutic agent, with satisfactory antibacterial properties.

Name	5,7-Diiodo-8-hydroxyquinoline
Synonym	More Synonyms

Description	Diiodohydroxyquinoline is a topical therapeutic agent, with satisfactory antibacterial properties.
Related Catalog	Signaling Pathways >> Anti-infection >> Bacterial Research Areas >> Infection

Density	2.5±0.1 g/cm3
Boiling Point	401.8±45.0 °C at 760 mmHg
Melting Point	>200 °C (dec.)(lit.)
Molecular Formula	C₉H₅I₂NO
Molecular Weight	396.951
Flash Point	196.8±28.7 °C
Exact Mass	396.846039
PSA	33.12000
LogP	4.11
Vapour Pressure	0.0±1.0 mmHg at 25°C
Index of Refraction	1.828

Diiodohydroxyquinoline MSDS(Chinese)

CHEMICAL IDENTIFICATION

RTECS NUMBER :: VC5775000

CHEMICAL NAME :: 8-Quinolinol, 5,7-diiodo-

CAS REGISTRY NUMBER :: 83-73-8

BEILSTEIN REFERENCE NO. :: 0153639

LAST UPDATED :: 199710

DATA ITEMS CITED :: 11

MOLECULAR FORMULA :: C9-H5-I2-N-O

MOLECULAR WEIGHT :: 396.95

WISWESSER LINE NOTATION :: T66 BNJ GI II JQ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - child

DOSE/DURATION :: 819 mg/kg/13D-I

TOXIC EFFECTS :: Behavioral - somnolence (general depressed activity) Behavioral - convulsions or effect on seizure threshold Blood - oxidant related (GPD deficient) anemia

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Human - child

DOSE/DURATION :: 120 gm/kg/2Y-I

TOXIC EFFECTS :: Sense Organs and Special Senses (Eye) - visual field changes

TYPE OF TEST :: LD - Lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: >40 gm/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 56 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Mammal - cat

DOSE/DURATION :: 300 mg/kg

TOXIC EFFECTS :: Liver - other changes

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - guinea pig

DOSE/DURATION :: 50 mg/kg

TOXIC EFFECTS :: Liver - other changes

MUTATION DATA

TEST SYSTEM :: Rodent - mouse

DOSE/DURATION :: 80 mg/kg

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 222,219,1989 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 80403 No. of Facilities: 68 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 2770 (estimated)

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H302-H318
Precautionary Statements	P280-P305 + P351 + P338
Hazard Codes	Xn: Harmful;
Risk Phrases	R22
Safety Phrases	S26-S36/37/39
RIDADR	3249
WGK Germany	3
RTECS	VC5775000
Packaging Group	III
Hazard Class	6.1(b)
HS Code	2933499090

8-Hydroxyquinoline

CAS#:148-24-3

~98%

Diiodohydroxyqu...

CAS#:83-73-8

Literature: Lista, Liliana; Pezzella, Alessandro; Napolitano, Alessandra; d'Ischia, Marco Tetrahedron, 2008 , vol. 64, # 1 p. 234 - 239

8-Hydroxyquinoline

CAS#:148-24-3

5-iodoquinolin-8-ol

CAS#:13207-63-1

Diiodohydroxyqu...

CAS#:83-73-8

Literature: Journal fuer Praktische Chemie (Leipzig), , vol. <2> 145, p. 257,261

1-(5,7-diiodoqu...

CAS#:220819-23-8

Diiodohydroxyqu...

CAS#:83-73-8

Succinic acid

CAS#:110-15-6

Metronidazole

CAS#:443-48-1

Detail

Literature: Scientia Pharmaceutica, , vol. 66, # 4 p. 309 - 324

1-(5,7-diiodoqu...

CAS#:220819-28-3

Diiodohydroxyqu...

CAS#:83-73-8

Phthalic acid

CAS#:88-99-3

Metronidazole

CAS#:443-48-1

Detail

Literature: Scientia Pharmaceutica, , vol. 66, # 4 p. 309 - 324

Hydrochloric acid

CAS#:7647-01-0

8-Hydroxyquinoline

CAS#:148-24-3

Water

CAS#:7732-18-5

Iodine monochloride

CAS#:7790-99-0

Detail

Literature: Journal of Organic Chemistry, , vol. 22, p. 1111

1,4-Dioxane

CAS#:123-91-1

Clioquinol

CAS#:130-26-7

Water

CAS#:7732-18-5

Chloroxine

CAS#:773-76-2

Detail

Literature: Chemische Berichte, , vol. 85, p. 104,106

HS Code	2933499090
Summary	2933499090. other compounds containing in the structure a quinoline or isoquinoline ring-system (whether or not hydrogenated), not further fused. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

Effects of oral administration of zinc and diiodohydroxyquinolein on plasma zinc levels of uremic patients.

Nephron 69(2) , 147-50, (1995)

Patients with chronic renal failure often have low plasma zinc (Zn) levels. Some factors that may account for abnormal Zn metabolism in these patients are low dietary Zn intake, a specific Zn transpor...

Chromatographic methods for simultaneous determination of diiodohydroxyquinoline and metronidazole in their binary mixture.

Pak. J. Pharm. Sci. 26(5) , 865-71, (2013)

Two chromatographic methods were developed for analysis ofdiiodohydroxyquinoline (DIHQ) and metronidazole (MTN). In the first method, diiodohydroxyquinoline and metronidazole were separated on TLC sil...

LC of pharmaceutically important halogenated 8-hydroxyquinolines after precolumn derivatization with Pd (II).

J. Pharm. Biomed. Anal. 27(5) , 813-20, (2002)

An accurate, sensitive, and selective reversed phase high performance liquid chromatographic (HPLC) method was developed for the analysis of two halogenated 8-hydroxyquinoline derivatives; clioquinol ...

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Shanghai Nianxing Industrial Co., Ltd
China
Product Name: Diiodohydroxyquinoline
Price: Click To Check
Purity: 98.0%
Delivery: 10 Day
Contact: Yang
Email: sales@echemcloud.com

Shanghai Jizhi Biochemical Technology Co., Ltd
China
Product Name: Diiodohydroxyquinoline
Price: ￥468.0/100g ￥168.0/25g
Purity: 98.0%
Delivery: 2 Day
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Email: 2130147988@qq.com

ShangHai DC Chemicals Co.,Ltd
China
Product Name: Iodoquinol
Price: ￥Inquiry/1g
Purity: 98.9%
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Email: order@dcchemicals.com

DC Chemicals Limited
China
Product Name: Iodoquinol
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/500mg
Purity: 98.0%
Delivery: 3 Day
Contact: Tony Cao
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Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: 5,7-Diiodo-8-quinolinol
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Henan Tianfu Chemical Co., Ltd.
China
Product Name: 5,7-Diiodo-8-quinolinol
Price: $Inquiry/1kg $Inquiry/25kg $Inquiry/1000kg $Inquiry/10ton
Purity: 99.0%
Delivery: Inquiry
Contact: Anson
Email: info@tianfuchem.com

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