![]() PL-017 structure
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Common Name | PL-017 | ||
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CAS Number | 83397-56-2 | Molecular Weight | 535.635 | |
Density | 1.3±0.1 g/cm3 | Boiling Point | 878.5±65.0 °C at 760 mmHg | |
Molecular Formula | C29H37N5O5 | Melting Point | N/A | |
MSDS | N/A | Flash Point | 485.1±34.3 °C |
Use of PL-017PL-017 is a potent and selective μ opioid receptor agonist with an IC50 of 5.5 nM for 125I-FK 33,824 binding to μ site. PL-017 produces long-lasting, reversible analgesia in rats[1]. |
Name | pl017 |
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Synonym | More Synonyms |
Description | PL-017 is a potent and selective μ opioid receptor agonist with an IC50 of 5.5 nM for 125I-FK 33,824 binding to μ site. PL-017 produces long-lasting, reversible analgesia in rats[1]. |
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Related Catalog | |
Target |
IC50: 5.5 nM (125I-FK 33,824 binding to μ site)[1] |
In Vitro | PL-017 has an IC50 of 10000 nM for 125I-DADLE binding to δ site[1]. |
In Vivo | PL-017 (0.22, 0.45, 0.9 nmol/rat; i.c.v.) has the time of maximum effect of approximately 15 to 30 mm after injection at lower doses and produces analgesia lasting as long as 4 hours with larger doses in male Sprague-Dawley rats weighing 250 to 375 g[1]. |
References |
Density | 1.3±0.1 g/cm3 |
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Boiling Point | 878.5±65.0 °C at 760 mmHg |
Molecular Formula | C29H37N5O5 |
Molecular Weight | 535.635 |
Flash Point | 485.1±34.3 °C |
Exact Mass | 535.279480 |
PSA | 150.27000 |
LogP | 0.93 |
Vapour Pressure | 0.0±0.3 mmHg at 25°C |
Index of Refraction | 1.630 |
Storage condition | -20°C |
Safety Phrases | 22-24/25 |
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