CAY10471 Racemate
Modify Date: 2024-01-03 17:21:21
CAY10471 Racemate structure
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Common Name | CAY10471 Racemate | ||
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| CAS Number | 844639-57-2 | Molecular Weight | 416.46600 | |
| Density | N/A | Boiling Point | N/A | |
| Molecular Formula | C21H21FN2O4S | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of CAY10471 RacemateCAY10471 Racemate (TM30089 Racemate) is a potent and highly selective prostaglandin D2 receptor CRTH2 antagonist, with a Ki of 0.6 nM for hCRTH2, selective over human thromboxane A2 receptor TP (Ki, >10000 nM) or PGD2 receptor DP (Ki, 1200 nM). CAY10471 Racemate also has effect on mouse and rat orthologs of CRTH2[1]. |
| Name | 9H-Carbazole-9-acetic acid, 3-[[(4-fluorophenyl)sulfonyl]methylamino]-1,2,3,4-tetrahydro |
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| Synonym | More Synonyms |
| Description | CAY10471 Racemate (TM30089 Racemate) is a potent and highly selective prostaglandin D2 receptor CRTH2 antagonist, with a Ki of 0.6 nM for hCRTH2, selective over human thromboxane A2 receptor TP (Ki, >10000 nM) or PGD2 receptor DP (Ki, 1200 nM). CAY10471 Racemate also has effect on mouse and rat orthologs of CRTH2[1]. |
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| Related Catalog | |
| Target |
Ki: 0.6 nM (CRTH2), 200 nM (DP)[1] |
| In Vitro | CAY10471 Racemate (Compound 13) inhibits PGD2-induced inositol phosphate or cAMP formatio, suppresses β-arrestin translocation with IC50s of 12 and 3 nM, respectively[1]. |
| References |
| Molecular Formula | C21H21FN2O4S |
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| Molecular Weight | 416.46600 |
| Exact Mass | 416.12100 |
| PSA | 87.99000 |
| LogP | 4.12380 |
| Storage condition | 2-8℃ |
| 3-[[(4-fluorophenyl)sulfonyl]methylamino]-1,2,3,4-tetrahydro-9h-carbazole-9-acetic acid |