Norgestrienone

Modify Date: 2024-01-03 10:41:45

Norgestrienone Structure
Norgestrienone structure
Common Name Norgestrienone
CAS Number 848-21-5 Molecular Weight 294.38700
Density 1.21g/cm3 Boiling Point 498.1ºC at 760 mmHg
Molecular Formula C20H22O2 Melting Point 169ºC
MSDS N/A Flash Point 211.2ºC

 Use of Norgestrienone


Norgestrienone, progestin or synthetic progestin, is a progestin receptor agonist. Norgestrienone is often used as a progestational compound in birth control pills and can be used in combination with ethinyl estradiol[1].

 Names

Name 17-Hydroxy-19-nor-17alpha-pregna-4,9,11-trien-20-yn-3-one
Synonym More Synonyms

 Norgestrienone Biological Activity

Description Norgestrienone, progestin or synthetic progestin, is a progestin receptor agonist. Norgestrienone is often used as a progestational compound in birth control pills and can be used in combination with ethinyl estradiol[1].
Related Catalog

 Chemical & Physical Properties

Density 1.21g/cm3
Boiling Point 498.1ºC at 760 mmHg
Melting Point 169ºC
Molecular Formula C20H22O2
Molecular Weight 294.38700
Flash Point 211.2ºC
Exact Mass 294.16200
PSA 37.30000
LogP 3.33270
Index of Refraction 1.615

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RC8960080
CHEMICAL NAME :
19-Nor-17-alpha-pregna-4,9,11-trien-20-yn-3-one, 17-hydroxy-
CAS REGISTRY NUMBER :
848-21-5
LAST UPDATED :
199706
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C20-H22-O2
MOLECULAR WEIGHT :
294.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
DOSE :
1168 ug/kg
SEX/DURATION :
female 52 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 18,411,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
DOSE :
1642 ug/kg
SEX/DURATION :
female 52 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 18,429,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravaginal
DOSE :
1 mg/kg
SEX/DURATION :
female 36 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 20,511,1979

 Synonyms

Ethynyl trienolone
Ogyline