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848-21-5

848-21-5 structure
848-21-5 structure
  • Name: Norgestrienone
  • Chemical Name: 17-Hydroxy-19-nor-17alpha-pregna-4,9,11-trien-20-yn-3-one
  • CAS Number: 848-21-5
  • Molecular Formula: C20H22O2
  • Molecular Weight: 294.38700
  • Catalog: API Hormone and endocrine-regulating drugs Estrogen and progestogen drugs
  • Create Date: 2018-02-10 08:00:00
  • Modify Date: 2024-01-03 10:41:45
  • Norgestrienone, progestin or synthetic progestin, is a progestin receptor agonist. Norgestrienone is often used as a progestational compound in birth control pills and can be used in combination with ethinyl estradiol[1].
Name 17-Hydroxy-19-nor-17alpha-pregna-4,9,11-trien-20-yn-3-one
Synonyms Ethynyl trienolone
Ogyline
Description Norgestrienone, progestin or synthetic progestin, is a progestin receptor agonist. Norgestrienone is often used as a progestational compound in birth control pills and can be used in combination with ethinyl estradiol[1].
Related Catalog
Density 1.21g/cm3
Boiling Point 498.1ºC at 760 mmHg
Melting Point 169ºC
Molecular Formula C20H22O2
Molecular Weight 294.38700
Flash Point 211.2ºC
Exact Mass 294.16200
PSA 37.30000
LogP 3.33270
Index of Refraction 1.615

CHEMICAL IDENTIFICATION

RTECS NUMBER :
RC8960080
CHEMICAL NAME :
19-Nor-17-alpha-pregna-4,9,11-trien-20-yn-3-one, 17-hydroxy-
CAS REGISTRY NUMBER :
848-21-5
LAST UPDATED :
199706
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C20-H22-O2
MOLECULAR WEIGHT :
294.42

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
DOSE :
1168 ug/kg
SEX/DURATION :
female 52 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Maternal Effects - menstrual cycle changes or disorders Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 18,411,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Implant
DOSE :
1642 ug/kg
SEX/DURATION :
female 52 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 18,429,1978
TYPE OF TEST :
TDLo - Lowest published toxic dose
ROUTE OF EXPOSURE :
Intravaginal
DOSE :
1 mg/kg
SEX/DURATION :
female 36 week(s) pre-mating
TOXIC EFFECTS :
Reproductive - Fertility - female fertility index (e.g. # females pregnant per # sperm positive females; # females pregnant per # females mated)
REFERENCE :
CCPTAY Contraception. (Geron-X, Inc., POB 1108, Los Altos, CA 94022) V.1- 1970- Volume(issue)/page/year: 20,511,1979

Chemsrc provides CAS#:848-21-5 MSDS, density, melting point, boiling point, structure, formula, molecular weight, synthetic route, etc.
title: CAS No. 848-21-5 | Chemsrc address: https://www.chemsrc.com/en/baike/947688.html

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