m-PEG4-Amine

Modify Date: 2024-01-08 17:57:02

m-PEG4-Amine structure	Common Name	m-PEG4-Amine
	CAS Number	85030-56-4	Molecular Weight	207.26700
	Density	1.005 g/cm3	Boiling Point	276.701ºC at 760 mmHg
	Molecular Formula	C₉H₂₁NO₄	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of m-PEG4-Amine

m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

Name	2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxy]ethanamine
Synonym	More Synonyms

Description	m-PEG4-Amine is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker
Target	Cleavable
In Vitro	ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
References	[1]. Hervé Bouchard, et al. Peptidic linkers and cryptophycin conjugates, useful in therapy, and their preparation. WO2018206635A1.

Density	1.005 g/cm3
Boiling Point	276.701ºC at 760 mmHg
Molecular Formula	C₉H₂₁NO₄
Molecular Weight	207.26700
Exact Mass	207.14700
PSA	62.94000
LogP	0.34160
Index of Refraction	1.439

m-PEG4-Amine MSDS(Chinese)

HS Code	2921199090

Tetraethylene g...

CAS#:23783-42-8

m-PEG4-Amine

CAS#:85030-56-4

Literature: Li, Guangtao; Bhosale, Sheshanath V.; Wang, Tianyu; Hackbarth, Steffen; Roeder, Beate; Siggel, Ulrich; Fuhrhop, Juergen-Hinrich Journal of the American Chemical Society, 2003 , vol. 125, # 35 p. 10693 - 10702

phthalimide

CAS#:136918-14-4

m-PEG3-OH

CAS#:112-35-6

m-PEG4-Amine

CAS#:85030-56-4

Literature: Tuchscherer, Andre; Schaarschmidt, Dieter; Schulze, Steffen; Hietschold, Michael; Lang, Heinrich European Journal of Inorganic Chemistry, 2011 , # 28 p. 4421 - 4428

m-PEG4-azide

CAS#:606130-90-9

~96%

m-PEG4-Amine

CAS#:85030-56-4

N/A

CAS#:199445-54-0

~65%

m-PEG4-Amine

CAS#:85030-56-4

Literature: Tuchscherer, Andre; Schaarschmidt, Dieter; Schulze, Steffen; Hietschold, Michael; Lang, Heinrich European Journal of Inorganic Chemistry, 2011 , # 28 p. 4421 - 4428

m-PEG4-Tos

CAS#:62921-76-0

m-PEG4-Amine

CAS#:85030-56-4

Literature: Bramson; Holmes; Hunter; Lackey; Lovejoy; Luzzio; Montana; Rocque; Rusnak; Shewchuk; Veal; Corona; Walker; Kuyper; Davis; Dickerson; Edelstein; Frye; Gampe Jr.; Harris; Hassell Journal of Medicinal Chemistry, 2001 , vol. 44, # 25 p. 4339 - 4358

Precursor 4
CAS#:606130-90-9 m-PEG4-azide CAS#:62921-76-0 m-PEG4-Tos CAS#:23783-42-8 Tetraethylene g... CAS#:112-35-6 m-PEG3-OH
DownStream 0

HS Code	2921199090
Summary	2921199090 other acyclic monoamines and their derivatives; salts thereof VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

3,6,9,12-Tetraoxatridecan-1-amine

tetra(ethylene glycol) methyl ether amine

2,6-DIMETHYLANILINE,[3H]

1-{2-[2-(2-methoxyethoxy)ethoxy]ethoxy}ethylamine

2,5,8,11-tetraoxatridecan-13-amine

2-{2-[2-(2-methoxyethoxy)-ethoxy]-ethoxy}-ethylamine

EINECS 285-182-1

3,6,9,12-Tetraoxatridecylamine

methylethertetraethyleneglycol amine

2-(2-(2-(2-methoxyethoxy)ethoxy)ethoxy)ethanamine

m-PEG4-Amine

Use of m-PEG4-Amine

Names

m-PEG4-Amine Biological Activity

Chemical & Physical Properties

MSDS

Safety Information

Synthetic Route

Precursor & DownStream

Customs

Synonyms