ERAP1-IN-1

Modify Date: 2024-01-11 16:30:09

ERAP1-IN-1 Structure
ERAP1-IN-1 structure
Common Name ERAP1-IN-1
CAS Number 865273-97-8 Molecular Weight 458.45
Density N/A Boiling Point N/A
Molecular Formula C20H21F3N2O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of ERAP1-IN-1


ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 competitively inhibits ERAP1 activity towards a nonamer peptide representative of physiological substrates[1].

 Names

Name ERAP1-IN-1

 ERAP1-IN-1 Biological Activity

Description ERAP1-IN-1 is an endoplasmic reticulum aminopeptidase 1 (ERAP1) inhibitor. ERAP1-IN-1 competitively inhibits ERAP1 activity towards a nonamer peptide representative of physiological substrates[1].
Related Catalog
Target

ERAP1[1]

In Vitro ERAP1-IN-1 allosterically activates ERAP1’s hydrolysis of fluorogenic and chromogenic amino acid substratesv[1]. ERAP1-IN-1 (50 µM) exhibits specific inhibition of ERAP1 in the cellular context[1].
References

[1]. Maben Z, et al. Discovery of Selective Inhibitors of Endoplasmic Reticulum Aminopeptidase 1. J Med Chem. 2019 Dec 30.

 Chemical & Physical Properties

Molecular Formula C20H21F3N2O5S
Molecular Weight 458.45

 Safety Information

Hazard Codes Xi
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