JTP-70902

Modify Date: 2024-01-16 16:51:28

JTP-70902 Structure
JTP-70902 structure
Common Name JTP-70902
CAS Number 871696-49-0 Molecular Weight 590.42100
Density N/A Boiling Point N/A
Molecular Formula C24H21BrFN5O5S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of JTP-70902


JTP-70902, a p15INK4b-inductive compound, is a MEK1/2 inhibitor. JTP-70902 exhibits potent antitumor effect[1].

 Names

Name N-[3-[5-(4-bromo-2-fluoroanilino)-3-cyclopropyl-8-methyl-2,4,7-trioxopyrido[2,3-d]pyrimidin-1-yl]phenyl]methanesulfonamide
Synonym More Synonyms

 JTP-70902 Biological Activity

Description JTP-70902, a p15INK4b-inductive compound, is a MEK1/2 inhibitor. JTP-70902 exhibits potent antitumor effect[1].
Related Catalog
References

[1]. Yamaguchi T, et, al. Identification of JTP-70902, a p15(INK4b)-inductive compound, as a novel MEK1/2 inhibitor. Cancer Sci. 2007 Nov;98(11):1809-16.  

 Chemical & Physical Properties

Molecular Formula C24H21BrFN5O5S
Molecular Weight 590.42100
Exact Mass 589.04300
PSA 132.58000
LogP 4.42950

 Synonyms

unii-sd93uqd78t