MEDICA 16

Modify Date: 2024-01-19 11:27:30

MEDICA 16 Structure
MEDICA 16 structure
Common Name MEDICA 16
CAS Number 87272-20-6 Molecular Weight 342.513
Density 1.0±0.1 g/cm3 Boiling Point 485.9±18.0 °C at 760 mmHg
Molecular Formula C20H38O4 Melting Point 154-159ºC
MSDS Chinese USA Flash Point 261.8±17.7 °C

 Use of MEDICA 16


MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle, and this reduction is accompanied by an increase in insulin sensitivity. MEDICA16 is a selective agonist for GPR40 as well as selective partial agonists for GPR120[1][2].

 Names

Name 3,3,14,14-tetramethylhexadecanedioic acid
Synonym More Synonyms

 MEDICA 16 Biological Activity

Description MEDICA16, an ATP-citrate lyase inhibitor, significantly reduces intracellular TG content in gastrocnemius muscle, and this reduction is accompanied by an increase in insulin sensitivity. MEDICA16 is a selective agonist for GPR40 as well as selective partial agonists for GPR120[1][2].
Related Catalog
References

[1]. Atkinson LL, et al. MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma triacylglycerol levels in insulin-resistant JCR: LA-cp rats. Diabetes. 2002;51(5):1548-1555.

[2]. Hara T, Hirasawa A, Sun Q, et al. Novel selective ligands for free fatty acid receptors GPR120 and GPR40. Naunyn Schmiedebergs Arch Pharmacol. 2009;380(3):247-255.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 485.9±18.0 °C at 760 mmHg
Melting Point 154-159ºC
Molecular Formula C20H38O4
Molecular Weight 342.513
Flash Point 261.8±17.7 °C
Exact Mass 342.277008
PSA 74.60000
LogP 6.44
Vapour Pressure 0.0±2.6 mmHg at 25°C
Index of Refraction 1.474

 Safety Information

HS Code 2917190090

 Synthetic Route

~%

MEDICA 16 Structure

MEDICA 16

CAS#:87272-20-6

Literature: WO2008/18877 A1, ; Page/Page column 20; 40-41 ;

 Precursor & DownStream

Precursor  1

DownStream  0

 Customs

HS Code 2917190090
Summary 2917190090 acyclic polycarboxylic acids, their anhydrides, halides, peroxides, peroxyacids and their derivatives VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:6.5% General tariff:30.0%

 Synonyms

3,3,14,14-Tetramethylhexanedecanedioic acid
3,3,14,14-tetramethyl-1,16-hexadecanedioic acid
MEDICA 16
Medic-16
3,3,14,14-tetramethyl-hexadecanedioic acid
3,3,14,14-Tetramethylhexadecanedioic acid
Hexadecandioic acid,3,3,14,14-tetramethyl
3,3,14,14-tetramethyl-hexadecane-1,16-dioic acid
Hexadecanedioic acid, 3,3,14,14-tetramethyl-
MFCD00797684
Top Suppliers:I want be here



Get all suppliers and price by the below link:

MEDICA 16 suppliers

MEDICA 16 price

Related Compounds: More...
heptadec-16-en-7-one
147492-48-6
diethyl (16-((tetrahydro-2H-pyran-2-yl)oxy)hexadec-6-en-8-yl)phosphonate
73881-16-0
hexapotassium 16,23-dihydronaphth[2',3':6,7]indolo[2,3-c]dinaphtho[2,3-a:2',3'-i]carbazole-5,10,15,17,22,24-hexyl hexasulphate
85098-60-8
Sodium (16,16,16-2H3)hexadecanoate
347841-37-6
QUATERNIUM-16
35239-12-4
15,16-Di-O-acetyldarutoside
1188282-02-1
15,16-o-(isopropylidene)-4,7,10,13-tetraoxa-hexadecylamine
869308-42-9
disodium 16,17-dimethoxyanthra[9,1,2-cde]benzo[rst]pentaphene-5,10-diyl bis(sulphate)
2538-84-3
7,16-Diphenyl-1,5,10,14-tetraazatricyclo[14.2.2.27,10]docosane
13073-16-0
2-[(2R)-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylbutanamido]-1-methylcyclopentane-1-carboxylic acid
2171439-68-0
(2S)-2-{[1-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-3-methylcyclohexyl]formamido}butanoic acid
2171339-05-0
(2S)-2-{[4-bromo-2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)phenyl]formamido}butanoic acid
2171154-37-1
(2S)-2-{2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)piperidin-1-yl]acetamido}butanoic acid
2171255-08-4
3-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)oxolane-3-carbonyl]-2-methyl-1,3-thiazolidine-4-carboxylic acid
2171582-08-2
(2S)-1-[3-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)cyclopentanecarbonyl]piperidine-2-carboxylic acid
2171311-41-2
2-[4-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-4-methylpentanamido]acetic acid
2171910-36-2
2-[5-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)-N-methylpentanamido]acetic acid
2171910-42-0
2-{2-[({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)methyl]-N-methylbutanamido}acetic acid
2172007-90-6
(2S)-2-[2-({[(9H-fluoren-9-yl)methoxy]carbonyl}amino)acetamido]-3-methylpentanoic acid
2648929-76-2