CHEMICAL IDENTIFICATION
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RTECS NUMBER :
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CL5446511
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CHEMICAL NAME :
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1-Azabicyclo(3.2.0)hept-2-ene-2-carboxylic acid, 6-(1-hydroxyethyl)-3-((1-(1-iminoethyl)- 3-pyrrolidinyl)thio)-7-oxo-, (5R-(3(S*),5-alpha,6-alpha(R*)))-
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CAS REGISTRY NUMBER :
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87726-17-8
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LAST UPDATED :
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199312
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DATA ITEMS CITED :
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2
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MOLECULAR FORMULA :
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C15-H21-N3-O4-S
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MOLECULAR WEIGHT :
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339.45
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
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TYPE OF TEST :
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LD50 - Lethal dose, 50 percent kill
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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1300 mg/kg
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TOXIC EFFECTS :
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Lungs, Thorax, or Respiration - dyspnea Lungs, Thorax, or Respiration - cyanosis
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REFERENCE :
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NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki, Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year: 39(Suppl 3),140,1991 ** OTHER MULTIPLE DOSE TOXICITY DATA **
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TYPE OF TEST :
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TDLo - Lowest published toxic dose
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ROUTE OF EXPOSURE :
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Intravenous
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SPECIES OBSERVED :
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Rodent - rat
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DOSE/DURATION :
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81 gm/kg/90D-I
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TOXIC EFFECTS :
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Blood - pigmented or nucleated red blood cells Biochemical - Enzyme inhibition, induction, or change in blood or tissue levels - phosphatases Related to Chronic Data - death
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REFERENCE :
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NKRZAZ Chemotherapy (Tokyo). (Nippon Kagaku Ryoho Gakkai, 2-20-8 Kamiosaki, Shinagawa-Ku, Tokyo 141, Japan) V.1- 1953- Volume(issue)/page/year: 39(Suppl 3),144,1991
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