NU-8231

Modify Date: 2024-01-03 15:36:00

NU-8231 Structure
NU-8231 structure
Common Name NU-8231
CAS Number 878022-36-7 Molecular Weight 467.95
Density N/A Boiling Point N/A
Molecular Formula C26H26ClNO5 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of NU-8231


A small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 5.3 uM in ELISA assay; induces p53-dependent gene transcription SJSA human sarcoma cell line.

 Names

Name NU-8231

 NU-8231 Biological Activity

Description A small molecule inhibitor of MDM2-p53 protein-protein interaction with IC50 of 5.3 uM in ELISA assay; induces p53-dependent gene transcription SJSA human sarcoma cell line.
References References 1. Hardcastle IR, et al. Bioorg Med Chem Lett. 2005 Mar 1;15(5):1515-20. 2. Hardcastle IR, et al. J Med Chem. 2011 Mar 10;54(5):1233-43. View Related Products by Target MDM2-p53

 Chemical & Physical Properties

Molecular Formula C26H26ClNO5
Molecular Weight 467.95
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