L-Leucine-d3

Modify Date: 2024-01-03 10:19:52

L-Leucine-d3 Structure
L-Leucine-d3 structure
Common Name L-Leucine-d3
CAS Number 87828-86-2 Molecular Weight 134.191
Density 1.0±0.1 g/cm3 Boiling Point 225.8±23.0 °C at 760 mmHg
Molecular Formula C6H10D3NO2 Melting Point >300ºC(lit.)
MSDS Chinese USA Flash Point 90.3±22.6 °C

 Use of L-Leucine-d3


L-Leucine-d3 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].

 Names

Name (2S)-2-amino-5,5,5-trideuterio-4-methylpentanoic acid
Synonym More Synonyms

 L-Leucine-d3 Biological Activity

Description L-Leucine-d3 is the deuterium labeled L-Leucine. L-Leucine is an essential branched-chain amino acid (BCAA), which activates the mTOR signaling pathway[1].
Related Catalog
In Vitro Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216.

 Chemical & Physical Properties

Density 1.0±0.1 g/cm3
Boiling Point 225.8±23.0 °C at 760 mmHg
Melting Point >300ºC(lit.)
Molecular Formula C6H10D3NO2
Molecular Weight 134.191
Flash Point 90.3±22.6 °C
Exact Mass 134.113464
PSA 63.32000
LogP 0.73
Vapour Pressure 0.0±0.9 mmHg at 25°C
Index of Refraction 1.463
Storage condition 2-8°C

 Safety Information

Personal Protective Equipment Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR NONH for all modes of transport

 Synonyms

(S)-Leucine-d3
L-Leucine-5,5,5-d3
L-Leucine-5,5,5-d
L-(5,5,5-H)Leucine
MFCD00144628
L-|A-Aminoisocaproic Acid-d3
L-Leucine-d3
(S)-2-Amino-4-methylvaleric Acid-d3
L-2-Amino-4-methylpentanoic Acid-d3
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