2’-Deoxy-N2,N2-dimethylguanosine

Modify Date: 2024-01-11 12:47:04

2’-Deoxy-N2,N2-dimethylguanosine Structure
2’-Deoxy-N2,N2-dimethylguanosine structure
Common Name 2’-Deoxy-N2,N2-dimethylguanosine
CAS Number 88127-22-4 Molecular Weight 295.29
Density N/A Boiling Point N/A
Molecular Formula C12H17N5O4 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of 2’-Deoxy-N2,N2-dimethylguanosine


2’-Deoxy-N2,N2-dimethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

 Names

Name 2-(dimethylamino)-9-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-3H-purin-6-one
Synonym More Synonyms

 2’-Deoxy-N2,N2-dimethylguanosine Biological Activity

Description 2’-Deoxy-N2,N2-dimethylguanosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

 Chemical & Physical Properties

Molecular Formula C12H17N5O4
Molecular Weight 295.29
Exact Mass 295.12800
PSA 116.76000

 Synonyms

Guanosine,2'-deoxy-N,N-dimethyl