DPDPE

Modify Date: 2024-01-06 10:32:31

DPDPE structure	Common Name	DPDPE
	CAS Number	88373-73-3	Molecular Weight	645.790
	Density	1.4±0.1 g/cm3	Boiling Point	1038.6±65.0 °C at 760 mmHg
	Molecular Formula	C₃₀H₃₉N₅O₇S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	581.9±34.3 °C

Use of DPDPE

DPDPE, an opioid peptide, is a selective δ-opioid receptor (DOR) agonist with anticonvulsant effects[1].

Name	13-[[2-amino-3-(4-hydroxyphenyl)propanoyl]amino]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid
Synonym	More Synonyms

Description	DPDPE, an opioid peptide, is a selective δ-opioid receptor (DOR) agonist with anticonvulsant effects[1].
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Opioid Receptor Signaling Pathways >> Neuronal Signaling >> Opioid Receptor Research Areas >> Neurological Disease
References	[1]. F C Tortella, et al. Anticonvulsant Effects of Mu (DAGO) and Delta (DPDPE) Enkephalins in Rats. Peptides

Density	1.4±0.1 g/cm3
Boiling Point	1038.6±65.0 °C at 760 mmHg
Molecular Formula	C₃₀H₃₉N₅O₇S₂
Molecular Weight	645.790
Flash Point	581.9±34.3 °C
Exact Mass	645.229065
PSA	250.55000
LogP	2.24
Vapour Pressure	0.0±0.3 mmHg at 25°C
Index of Refraction	1.653
Storage condition	-20°C

WGK Germany	3

[D-Pen2,5]enkephalin

CAS#:100111-01-1

~64%

DPDPE

CAS#:88373-73-3

Literature: Maruyama, Toshihiro; Ikeo, Takayoshi; Ueki, Masaaki Tetrahedron Letters, 1999 , vol. 40, # 27 p. 5031 - 5034

Boc-Gly-OH

CAS#:4530-20-5

Boc-L-phenylalanine

CAS#:13734-34-4

Boc-Tyr-OH

CAS#:3978-80-1

N/A

CAS#:115962-34-0

Detail

Literature: Journal of the American Chemical Society, , vol. 118, # 31 p. 7280 - 7290

Precursor 4
CAS#:100111-01-1 [D-Pen2,5]enkephalin CAS#:4530-20-5 Boc-Gly-OH CAS#:13734-34-4 Boc-L-phenylalanine CAS#:3978-80-1 Boc-Tyr-OH
DownStream 0

c[D-Pen2,5]-enkephalin

[D-Pen(2),D-Pen(5)]enkephalin

8-(3-Chlorostyryl)caffeine

1,2-Dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid, 13-[[(2S)-2-amino-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-3,3,14,14-tetramethyl-6,9,12-trioxo-7-(phenylmethyl)-, (4S,7S,13S)-

Tyr-D-Pen-Gly-Phe-D-Pen

(4S,7S,13S)-7-Benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-13-(L-tyrosylamino)-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid

H-Tyr-c(D-Pen-Gly-Phe-D-Pen)-OH

DPDPE

13-[2-amino-3-(4-hydroxyphenyl)propanamido]-7-benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid

1,2-Dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid, 13-[[(2S)-2-amino-3-(4-hydroxyphenyl)-1-oxopropyl]amino]-3,3,14,14-tetramethyl-6,9,12-trioxo-7-(phenylmethyl)-, (4R,7S,13R)-

Tyr-c[D-Pen-Gly-Phe-D-Pen]OH

(4R,7S,13R)-7-Benzyl-3,3,14,14-tetramethyl-6,9,12-trioxo-13-(L-tyrosylamino)-1,2-dithia-5,8,11-triazacyclotetradecane-4-carboxylic acid

[D-Pen2,5]-ENKEPHALIN

[D-Pen2-D-Pen5]-enkephaline

c[D-Pen(2)-D-Pen(5)]enkephalin