[D-Pro4,D-Trp7,9,Nle11]-Substance P (4-11)

Modify Date: 2024-01-12 14:49:18

[D-Pro4,D-Trp7,9,Nle11]-Substance P (4-11) structure	Common Name	[D-Pro4,D-Trp7,9,Nle11]-Substance P (4-11)
	CAS Number	89430-34-2	Molecular Weight	1116.31000
	Density	N/A	Boiling Point	N/A
	Molecular Formula	C₅₈H₇₇N₁₃O₁₀	Melting Point	N/A
	MSDS	USA	Flash Point	N/A

Use of [D-Pro4,D-Trp7,9,Nle11]-Substance P (4-11)

[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist. [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) inhibits the effects of gold-protein-substance P (GPSP) and substance P (SP)[1].

Name	[D-Pro4,D-Trp7,9,Nle11]-Substance P (4-11)
Synonym	More Synonyms

Description	[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) is a potent neurokinin NK1 antagonist. [D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) inhibits the effects of gold-protein-substance P (GPSP) and substance P (SP)[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Research Areas >> Neurological Disease Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor
In Vitro	[D-Pro4,D-Trp7,9,Nle11] Substance P (4-11) (100 nM) dose not exert a direct relaxant or contractile effect, but significantly reduces the vasodilatation induced by SP and GPSP[1].
References	[1]. Cathieni M M, et al. Pharmacological Evidence that Gold-Protein-Substance P Complex Activates Neurokinin NK1 Receptors[J]. Cellular Physiology & Biochemistry, 1995, 5(2):85-95.

Molecular Formula	C₅₈H₇₇N₁₃O₁₀
Molecular Weight	1116.31000
Exact Mass	1115.59000
PSA	376.58000
LogP	6.24130

MSDS(Chinese)

Personal Protective Equipment	Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
RIDADR	NONH for all modes of transport
WGK Germany	3

A new analogue of substance P with antagonistic properties in renal and pulmonary arteries.

Acta Physiol. 15 , 10, (1989)

The effects of a new analogue of substance P (SP-A) and its interaction with substance P (SP) were studied in vitro isolated preparations from rabbit renal arteries and rat renal and pulmonary arterie...

Synthesis of substance P antagonists: [D-Pro4, D-Trp7,9,Nle11]-substance P(4-11).

Pharmazie 39(1) , 65-7, (1984)

4-Pro-7,9-Trp-11-nle-substance p (4-11)

substance P (4-11),Pro(4)-Trp(7,9)-Nle(11)

Substance P,fragment 4-11,[D-Pro4,D-Trp7,9,Nle11]

(D-pro4,D-trp7,9,nle11)-substance P*fragment 4-11

Pttnl-sp(4-11)

H-D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-NLE-NH2

SUBSTANCE P [D-PRO4,D-TRP7,9,NLE11]-FRAGMENT 4-11

D-Pro-L-Gln-L-Gln-D-Trp-L-Phe-D-Trp-L-Leu-L-Nle-NH2

(D-PRO4,D-TRP7,9,NLE11)-SUBSTANCE P (4-11)

D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-NLE-NH2

GL Biochem (Shanghai) Ltd.
China
Product Name: [D-Pro4,D-Trp7,9,Nle11]-Substance P (4-11)
Price: $Inquiry/1g
Purity: 98.0%
Delivery: Inquiry
Contact: Jackie Yang
Email: ymbetter@glbiochem.com

Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: D-PRO-GLN-GLN-D-TRP-PHE-D-TRP-LEU-NLE-NH2
Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
Purity: 98.0%
Delivery: Inquiry
Contact: Ms Wang
Email: enquiry@dycnchem.com

Taiwan Oyi peptide Co. Ltd
China
Product Name: [D-Pro4,D-Trp7,9,Nle11]-Substance P (4-11)
Price: $Inquiry/1mg $Inquiry/100kg
Purity: 98.0%
Delivery: 1 Day
Contact: Vinnie
Email: Jamie@api-made.com

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