Xanthone

Modify Date: 2024-01-02 11:32:57

Xanthone Structure
Xanthone structure
Common Name Xanthone
CAS Number 90-47-1 Molecular Weight 196.201
Density 1.3±0.1 g/cm3 Boiling Point 350.0±12.0 °C at 760 mmHg
Molecular Formula C13H8O2 Melting Point 172-174 °C(lit.)
MSDS USA Flash Point 169.8±13.1 °C
Symbol GHS06
GHS06
Signal Word Danger

 Use of Xanthone


Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities[1].

 Names

Name xanthone
Synonym More Synonyms

 Xanthone Biological Activity

Description Xanthone is isolated from Mangosteen and is known to control cell division and growth, apoptosis, inflammation, and metastasis in different stages of carcinogenesis. Xanthone has anti-oxidant, anti-tumor, anti-allergic, anti-inflammatory, anti-bacterial, anti-fungal, and anti-viral activities[1].
Related Catalog
References

[1]. Shan T, et al.Xanthones from mangosteen extracts as natural chemopreventive agents: potential anticancerdrugs. Curr Mol Med. 2011 Nov;11(8):666-77.

 Chemical & Physical Properties

Density 1.3±0.1 g/cm3
Boiling Point 350.0±12.0 °C at 760 mmHg
Melting Point 172-174 °C(lit.)
Molecular Formula C13H8O2
Molecular Weight 196.201
Flash Point 169.8±13.1 °C
Exact Mass 196.052429
PSA 30.21000
LogP 3.39
Vapour Pressure 0.0±0.8 mmHg at 25°C
Index of Refraction 1.643
Stability Stable. Incompatible with strong oxidizing agents.

 Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
ZD5711000
CHEMICAL NAME :
Xanthen-9-one
CAS REGISTRY NUMBER :
90-47-1
LAST UPDATED :
199803
DATA ITEMS CITED :
3
MOLECULAR FORMULA :
C13-H8-O2
MOLECULAR WEIGHT :
196.21
WISWESSER LINE NOTATION :
T C666 BO IVJ

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD - Lethal dose
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
NCNSA6 National Academy of Sciences, National Research Council, Chemical-Biological Coordination Center, Review. (Washington, DC) Volume(issue)/page/year: 5,25,1953
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
180 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
CSLNX* U.S. Army Armament Research & Development Command, Chemical Systems Laboratory, NIOSH Exchange Chemicals. (Aberdeen Proving Ground, MD 21010) Volume(issue)/page/year: NX#01611

 Safety Information

Symbol GHS06
GHS06
Signal Word Danger
Hazard Statements H301
Precautionary Statements Missing Phrase - N15.00950417
Personal Protective Equipment dust mask type N95 (US);Eyeshields;Faceshields;Gloves
Hazard Codes Xi: Irritant;Xn: Harmful;
Risk Phrases R22
Safety Phrases S24/25
RIDADR UN 2811 6.1/PG 3
WGK Germany 3
RTECS ZD5711000
HS Code 2932999099

 Synthetic Route

 Customs

HS Code 2932999099
Summary 2932999099. other heterocyclic compounds with oxygen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%

 Articles33

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 Synonyms

Xanthone
Dibenzo-g-pyrone
Benzophenone oxide
9-Xanthenone
MFCD00005060
9H-Xanthen-9-one
9-Oxoxanthene
Genicide
Diphenylene ketone oxide
Xanthenone
EINECS 201-997-7
xanthen-9-one
Dibenzo-γ-pyrone
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