UBP 310

Modify Date: 2024-01-02 22:42:07

UBP 310 Structure
UBP 310 structure
Common Name UBP 310
CAS Number 902464-46-4 Molecular Weight 353.35000
Density N/A Boiling Point N/A
Molecular Formula C14H15N3O6S Melting Point N/A
MSDS N/A Flash Point N/A

 Use of UBP 310


UBP310 is a selective GluR5 antagonist, with a Kd of 130 nM[1].

 Names

Name 1(2H)-Pyrimidinepropanoic acid, α-amino-3-[(2-carboxy-3-thienyl)methyl]-3,4-dihydro-5-methyl-2,4-dioxo-, (αS)

 UBP 310 Biological Activity

Description UBP310 is a selective GluR5 antagonist, with a Kd of 130 nM[1].
Related Catalog
Target

GluR5[1]

In Vitro UBP310 binds to GluR5 S1S2 with an affinity of 130 nM and shows 12,700-fold selectivity for GluR5 versus GluR6 and 830-fold selectivity for GluR5 versus GluR2[1].
References

[1]. Mark L Mayer, et al. Crystal structures of the kainate receptor GluR5 ligand binding core dimer with novel GluR5-selective antagonists. J Neurosci. 2006 Mar 15;26(11):2852-61.

 Chemical & Physical Properties

Molecular Formula C14H15N3O6S
Molecular Weight 353.35000
Exact Mass 353.06800
PSA 172.86000
LogP 0.23860