Neochamaejasmin A

Modify Date: 2024-01-05 16:09:59

Neochamaejasmin A Structure
Neochamaejasmin A structure
Common Name Neochamaejasmin A
CAS Number 90411-13-5 Molecular Weight 542.49000
Density 1.594±0.06 g/cm3 Boiling Point N/A
Molecular Formula C30H22O10 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of Neochamaejasmin A


Neochamaejasmine A is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L.. Neochamaejasmine A inhibits proliferation, induces cell cycle arrest and Apoptosis in tumor cells. Neochamaejasmine A can be used in the research of cancers such as prostate cancer, hepatoma cancer[1][2].

 Names

Name (+)-chamaejasmin
Synonym More Synonyms

 Neochamaejasmin A Biological Activity

Description Neochamaejasmine A is a biflavonoid that can be isolated from the roots of Stellera chamaejasme L.. Neochamaejasmine A inhibits proliferation, induces cell cycle arrest and Apoptosis in tumor cells. Neochamaejasmine A can be used in the research of cancers such as prostate cancer, hepatoma cancer[1][2].
Related Catalog
References

[1]. Liu WK, et al. Involvement of p21 and FasL in induction of cell cycle arrest and apoptosis by neochamaejasmin A in human prostate LNCaP cancer cells. J Nat Prod. 2008 May;71(5):842-6.  

[2]. Ding Y, et al. Neochamaejasmin A Induces Mitochondrial-Mediated Apoptosis in Human Hepatoma Cells via ROS-Dependent Activation of the ERK1/2/JNK Signaling Pathway. Oxid Med Cell Longev. 2020 Jan 20;2020:3237150.  

 Chemical & Physical Properties

Density 1.594±0.06 g/cm3
Molecular Formula C30H22O10
Molecular Weight 542.49000
Exact Mass 542.12100
PSA 173.98000
LogP 4.48560
Water Solubility Insuluble (1.0E-4 g/L) (25 ºC)

 Synonyms

Neochamaejasmin A