Carebastine
Modify Date: 2024-01-02 23:31:17
Carebastine structure
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Common Name | Carebastine | ||
|---|---|---|---|---|
| CAS Number | 90729-42-3 | Molecular Weight | 499.641 | |
| Density | 1.2±0.1 g/cm3 | Boiling Point | 657.9±55.0 °C at 760 mmHg | |
| Molecular Formula | C32H37NO4 | Melting Point | 178-180ºC | |
| MSDS | N/A | Flash Point | 351.7±31.5 °C | |
Use of CarebastineCarebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner[1]. Carebastine suppresses the expression of macrophage migration inhibitory factor[2]. |
| Name | 2-[4-[4-(4-benzhydryloxypiperidin-1-yl)butanoyl]phenyl]-2-methylpropanoic acid |
|---|---|
| Synonym | More Synonyms |
| Description | Carebastine is the active metabolite of Ebastine. Carebastine is a histamine H1 receptor antagonist. Carebastine inhibits VEGF-induced HUVEC and HPAEC proliferation, migration and angiogenesis in a dose-dependent manner[1]. Carebastine suppresses the expression of macrophage migration inhibitory factor[2]. |
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| Related Catalog | |
| Target |
H1 receptor |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 657.9±55.0 °C at 760 mmHg |
| Melting Point | 178-180ºC |
| Molecular Formula | C32H37NO4 |
| Molecular Weight | 499.641 |
| Flash Point | 351.7±31.5 °C |
| Exact Mass | 499.272247 |
| PSA | 66.84000 |
| LogP | 6.09 |
| Vapour Pressure | 0.0±2.1 mmHg at 25°C |
| Index of Refraction | 1.609 |
| p-(4-(4-(Diphenylmethoxy)piperidino)butyryl)-a-methylhydratropic Acid |
| Carebastinum |
| carebastine |
| 2-(4-{4-[4-(Diphenylmethoxy)piperidin-1-yl]butanoyl}phenyl)-2-methylpropanoic acid |
| 4-(4-(4-(Diphenylmethoxy)-1-piperidinyl)-1-oxobutyl)-a,a-dimethylbenzeneacetic Acid |
| Benzeneacetic acid, 4-[4-[4-(diphenylmethoxy)-1-piperidinyl]-1-oxobutyl]-α,α-dimethyl- |
| Carebastina |
| C32H37NO4 |
| UNII-75DLN707DO |
| 2-(4-{4-[4-(Diphenylmethoxy)-1-piperidinyl]butanoyl}phenyl)-2-methylpropanoic acid |