TC-I 15

Modify Date: 2024-01-12 18:08:41

TC-I 15 structure	Common Name	TC-I 15
	CAS Number	916734-43-5	Molecular Weight	520.62
	Density	1.364±0.06 g/cm3 (20 °C, 760 mmHg)	Boiling Point	N/A
	Molecular Formula	C₂₃H₂₈N₄O₆S₂	Melting Point	N/A
	MSDS	N/A	Flash Point	N/A

Use of TC-I 15

TC-I 15 (TC-I-15) is an allosteric, collagen-binding integrin α2β1 inhibitor with IC50 values of 26.8 μM and 0.4 μM for GFOGER and GLOGEN, respectively. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition[1].

Name	L-Alanine, N-[[(4R)-5,5-dimethyl-3-(phenylsulfonyl)-4-thiazolidinyl]carbonyl]-3-[[[(phenylmethyl)amino]carbonyl]amino]
Synonym	More Synonyms

Description	TC-I 15 (TC-I-15) is an allosteric, collagen-binding integrin α2β1 inhibitor with IC50 values of 26.8 μM and 0.4 μM for GFOGER and GLOGEN, respectively. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition[1].
Related Catalog	Research Areas >> Cardiovascular Disease Signaling Pathways >> Cytoskeleton >> Integrin
Target	α2β1:0.4 (α2β1 μM (IC50) α2β1:26.8 (α2β1 μM (IC50) α1β1:23.6 (α1β1 μM (IC50) α1β1:24.4 (α1β1 μM (IC50) α11β1:177 (α11β1 μM (IC50) α11β1:3177 (α11β μM (IC50)
References	[1]. Emma J. Hunter, Selectivity of the collagen-binding integrin inhibitors, TC-I-15 and obtustatin. Toxicol Appl Pharmacol. 2021 Oct 1;428:115669.

Density	1.364±0.06 g/cm3 (20 °C, 760 mmHg)
Molecular Formula	C₂₃H₂₈N₄O₆S₂
Molecular Weight	520.62
Exact Mass	520.14500
PSA	178.59000
LogP	3.78900

Piclamilast

DC Chemicals Limited
China
Product Name: α2β1 integrin-IN-15
Price: $Inquiry/100mg $Inquiry/250mg $Inquiry/1g
Purity: 98.0%
Stocking Period: 3 Day
Contact: Tony Cao

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TC-I 15

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