TC-I 15
Modify Date: 2024-01-12 18:08:41
TC-I 15 structure
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Common Name | TC-I 15 | ||
|---|---|---|---|---|
| CAS Number | 916734-43-5 | Molecular Weight | 520.62 | |
| Density | 1.364±0.06 g/cm3 (20 °C, 760 mmHg) | Boiling Point | N/A | |
| Molecular Formula | C23H28N4O6S2 | Melting Point | N/A | |
| MSDS | N/A | Flash Point | N/A | |
Use of TC-I 15TC-I 15 (TC-I-15) is an allosteric, collagen-binding integrin α2β1 inhibitor with IC50 values of 26.8 μM and 0.4 μM for GFOGER and GLOGEN, respectively. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition[1]. |
| Name | L-Alanine, N-[[(4R)-5,5-dimethyl-3-(phenylsulfonyl)-4-thiazolidinyl]carbonyl]-3-[[[(phenylmethyl)amino]carbonyl]amino] |
|---|---|
| Synonym | More Synonyms |
| Description | TC-I 15 (TC-I-15) is an allosteric, collagen-binding integrin α2β1 inhibitor with IC50 values of 26.8 μM and 0.4 μM for GFOGER and GLOGEN, respectively. TC-I 15 inhibits platelet adhesion to collagen and thrombus deposition[1]. |
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| Related Catalog | |
| Target |
α2β1:0.4 (α2β1 μM (IC50) α2β1:26.8 (α2β1 μM (IC50) α1β1:23.6 (α1β1 μM (IC50) α1β1:24.4 (α1β1 μM (IC50) α11β1:177 (α11β1 μM (IC50) α11β1:3177 (α11β μM (IC50) |
| References |
| Density | 1.364±0.06 g/cm3 (20 °C, 760 mmHg) |
|---|---|
| Molecular Formula | C23H28N4O6S2 |
| Molecular Weight | 520.62 |
| Exact Mass | 520.14500 |
| PSA | 178.59000 |
| LogP | 3.78900 |
| Piclamilast |