t-Boc-Aminooxy-PEG3-bromide

Modify Date: 2024-01-11 13:05:30

t-Boc-Aminooxy-PEG3-bromide Structure
t-Boc-Aminooxy-PEG3-bromide structure
Common Name t-Boc-Aminooxy-PEG3-bromide
CAS Number 918132-15-7 Molecular Weight 372.25
Density N/A Boiling Point N/A
Molecular Formula C13H26BrNO6 Melting Point N/A
MSDS N/A Flash Point N/A

 Use of t-Boc-Aminooxy-PEG3-bromide


Boc-Aminooxy-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

 Names

Name Boc-Aminooxy-PEG3-bromide
Synonym More Synonyms

 t-Boc-Aminooxy-PEG3-bromide Biological Activity

Description Boc-Aminooxy-PEG3-bromide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

PEGs

Alkyl/ether

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. Zhao B, et al. Protein Engineering in the Ubiquitin System: Tools for Discovery and Beyond. Pharmacol Rev. 2020 Apr;72(2):380-413.

 Chemical & Physical Properties

Molecular Formula C13H26BrNO6
Molecular Weight 372.25

 Synonyms

MFCD29764337
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