Shanghai Nianxing Industrial Co., Ltd
China
Product Name: t-Boc-Aminooxy-PEG4-NHS ester
Price:
Purity: 98.0%
Stocking Period: 10 Day
Contact: Yang

2401831-99-8

2401831-99-8 structure

2401831-99-8 structure

Name: t-Boc-Aminooxy-PEG4-NHS ester
Chemical Name: t-Boc-Aminooxy-PEG4-NHS ester
CAS Number: 2401831-99-8
Molecular Formula: C₂₀H₃₄N₂O₁₁
Molecular Weight: 478.49
Catalog: Signaling Pathways PROTAC PROTAC Linker
Create Date: 2020-06-01 19:51:52
Modify Date: 2024-01-12 08:06:40
t-Boc-Aminooxy-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name	t-Boc-Aminooxy-PEG4-NHS ester

Description	t-Boc-Aminooxy-PEG4-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> PROTAC >> PROTAC Linker
Target	PEGs Alkyl/ether
In Vitro	PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References	[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562

Molecular Formula	C₂₀H₃₄N₂O₁₁
Molecular Weight	478.49